Rh(III)-Catalyzed Oxidative Coupling of N-Aryl-2-aminopyridine with Alkynes and Alkenes

被引：212
|
作者：
Chen, Jinlei [2 ]
Song, Guoyong [1 ]
Pan, Cheng-Ling [1 ]
Li, Xingwei [1 ]
机构：
[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
[2] Jilin Univ, State Key Lab Theoret & Computat Chem, Changchun 130023, Peoples R China
来源：
ORGANIC LETTERS | 2010年 / 12卷 / 23期
关键词：
C-H BOND; INTERNAL ALKYNES; BENZOIC-ACIDS; ACTIVATION; RH; FUNCTIONALIZATION; CLEAVAGE; COUPLING/CYCLIZATION; CARBON; BENZAMIDES;
D O I：
10.1021/ol1022596
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[RhCp*Cl-2](2) (1-2 mol %) can catalyze the oxidative coupling of N-aryl-2-aminopyridines with alkynes and arylates to give N-(2-pyridyl)indoles and N-(2-pyridyl)quinolones, respectively, using Cu(OAc)(2) as an oxidant. Coupling with styrenes gave mono- and/or disubstituted olefination products.
引用
收藏
页码：5426 / 5429
页数：4
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