Practical considerations in the making and use of high-dose antibiotic-loaded bone cement

被引：0
|
作者：
Samuel, Sumant [1 ]
Ismavel, Ravichand [1 ]
Boopalan, P. R. J. V. C. [1 ]
Matthai, Thomas [1 ]
机构：
[1] Christian Med Coll & Hosp, Dept Orthopaed, Unit 3, Vellore 632004, Tamil Nadu, India
来源：
ACTA ORTHOPAEDICA BELGICA | 2010年 / 76卷 / 04期
关键词：
antibiotic bone cement; beads; preparation; antibiotic elution; ELUTION CHARACTERISTICS; VANCOMYCIN; INFECTION; GENTAMICIN; TOBRAMYCIN; DELIVERY;
D O I：
暂无
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Local antibiotic delivery with antibiotic loaded acrylic bone cement has been used extensively in the management of chronic osteomyelitis and implant related infections. Though newer drug delivery vehicles are being investigated, it remains the most widely used local antibiotic delivery vehicle in orthopaedic surgery. Self- made antibiotic loaded bone cement beads, which are cheaper and antibiotic specific, have been shown to elute less effectively than commercial antibiotic loaded cement beads. We offer several tips for increasing the elution and effectiveness of antibiotic loaded bone cement in clinical practice.
引用
收藏
页码：543 / 545
页数：3
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