Correlations between peripapillary retinal nerve fiber layer thickness and macular thickness in different various stages of primary open-angle glaucoma

Purpose. - To determine the relationship between macular thickness and peripapillary retinal nerve fiber layer (RNFLp) thickness in different stages of primary open-angle glaucoma (POAG). Methods. - Ninety prospectively selected patients with different stage POAG underwent spectral domain optical coherence tomography (SD-OCT) to determine macular and RNFLp thicknesses in different regions and sectors respectively. Correlations were then established through Pearson's correlation coefficient between RNFLp and macular thicknesses in the different disease stages. Results. - Greatest correlation was observed between the inferior RNFLp sector and the internal inferior macula both in the whole patient population and in the subset of patients with incipient glaucoma. Conclusions. - When the optic nerve disc is affected by another condition, macular thickness determination may help detect POAG and monitor its progression. (C) 2018 Elsevier Masson SAS. All rights reserved.