Isolated ACTH Deficiency Presenting with a Glucocorticoid-Responsive Triphasic Wave Coma

被引：4

作者：

Sugita, Toshihisa ^{[1
,2
]}

Nakajima, Masashi ^{[1
]}

Arai, Daisuke ^{[2
]}

Kuwabara, Kohichiro ^{[3
]}

Kawamura, Mitsuru ^{[1
]}

机构：

[1] Showa Univ, Dept Neurol, Sch Med, Tokyo, Japan

[2] Tokyo Rosai Occupat Dis & Injuries Hosp, Dept Neurol, Tokyo, Japan

[3] Tokyo Rosai Occupat Dis & Injuries Hosp, Dept Internal Med, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2012年 / 51卷 / 14期

关键词：

ACTH deficiency; coma; electroencephalography; glucocorticoid; triphasic waves; NONCONVULSIVE STATUS EPILEPTICUS; EEG;

D O I：

10.2169/internalmedicine.51.7469

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the case of a 58-year-old woman who presented with acutely developed coma characterized by electroencephalographic triphasic waves (TWs) in the absence of metabolic derangement. The patient's coma and TWs were promptly resolved after the administration of glucocorticoids, and thereafter isolated ACTH deficiency was diagnosed. Isolated ACTH deficiency may present with glucocorticoid-responsive acute encephalopathy without hypoglycemia, hyponatremia, or systemic hypotension. Electroencephalographic TWs or bursts of slow waves may be a clue to the diagnosis of this rare condition in patients with coma of unknown origin.

引用

页码：1913 / 1915

页数：3

共 27 条

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[25] Case report: three patients presenting with isolated ACTH deficiency caused most likely by hypophysitis, traumatic brain injury and empty sella syndrome v
Mueller-Oeffner, A.
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EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 2013, 121 (03)
[26] Presenting Features, Clinical Characteristics and Follow Up of Familial Isolated Glucocorticoid Deficiency (FGD) Due to Mutations in MC2R and MRAP Genes
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Karasin, Nezehat Dogan
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HORMONE RESEARCH IN PAEDIATRICS, 2018, 90 : 161 - 162
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