A Near-Infrared Fluorescence Probe for Thiols Based on Analyte-Specific Cleavage of Carbamate and Its Application in Bioimaging

被引：32

作者：

Zhang, Jianjian ^{[1
,2
]}

Yu, Bianfei ^{[1
,2
]}

Ning, Lulu ^{[1
,2
]}

Zhu, Xinyue ^{[1
,2
]}

Wang, Jianxi ^{[1
,2
]}

Chen, Zhenjie ^{[3
]}

Liu, Xiaoyan ^{[1
,2
]}

Yao, Xiaojun ^{[1
,2
]}

Zhang, Xiaoyu ^{[3
]}

Zhang, Haixia ^{[1
,2
]}

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China

[3] Lanzhou Univ, Inst Physiol, Sch Basic Med Sci, Lanzhou 730000, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 2015卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Dyes; pigments; Imaging agents; Fluorescent probes; Cyanines; Thiols; RECENT PROGRESS; COLORIMETRIC CHEMOSENSORS; SELECTIVE DETECTION; OXIDATIVE STRESS; GLUTATHIONE; CYSTEINE; HOMOCYSTEINE; LUMINESCENT; SENSORS; DESIGN;

D O I：

10.1002/ejoc.201403398

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

With increasing interest in optical in vivo imaging, there is a corresponding increase in demand for near-infrared (NIR) dyes. Such probes can be used, for example, to detect intracellular GSH, which would be helpful for understanding the mechanisms of diseases. In this work, we report a cyanine-based fluorescent probe that undergoes biothiol-promoted specific O-S cleavage and subsequent self-immolation through intramolecular 1,6-elimination. In addition, we investigated the cell viability of the system and successfully applied the probe to living cells, in vivo, and in various tissues.

引用

页码：1711 / 1718

页数：8

共 50 条

[11] A salicylaldehyde benzoyl hydrazone based near-infrared probe for copper(ii) and its bioimaging applications
Zhao, Jie
Wang, Yue-yuan
Chen, Wen-ling
Hao, Guang-shu
Sun, Jian-ping
Shi, Qing-fang
Tian, Fang
Ma, Run-tian
RSC ADVANCES, 2022, 12 (05) : 3073 - 3080
[12] A near-infrared fluorescence probe for hydrazine based on dicyanoisophorone
Zhang, Shiqing
Chen, Daiwen
Yan, Liqiang
Xie, Ya
Mu, Xinyue
Zhu, Jinbiao
MICROCHEMICAL JOURNAL, 2020, 157
[13] Construction of a Near-Infrared Fluorescent Turn-On Probe for Selenol and Its Bioimaging Application in Living Animals
Chen, Hua
Dong, Baoli
Tang, Yonghe
Lin, Weiying
CHEMISTRY-A EUROPEAN JOURNAL, 2015, 21 (33) : 11696 - 11700
[14] A novel near-infrared ratiometric fluorescent probe for cyanide and its bioimaging applications
Kang, Jin
Huo, Fangjun
Zhang, Yongbin
Chao, Jianbin
Glass, Timothy E.
Yin, Caixia
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2019, 209 : 95 - 99
[15] A BODIPY-based "turn on" near-infrared fluorescence probe for specific detection of cysteine
Dou, Xiaozong
Liu, Weiqi
Luo, Yuhui
Zhang, Li
Luo, Jia
Wu, Chenfeng
Huang, Tiejun
Pu, Xingling
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 327
[16] Near-infrared laser scanning confocal microscopy and its application in bioimaging
Sun, Chaowei
Wang, Yalun
Zhang, Hequn
Qian, Jun
OPTICAL AND QUANTUM ELECTRONICS, 2018, 50 (01)
[17] Near-infrared laser scanning confocal microscopy and its application in bioimaging
Chaowei Sun
Yalun Wang
Hequn Zhang
Jun Qian
Optical and Quantum Electronics, 2018, 50
[18] A near-infrared turn on fluorescent probe for specific detection of cysteine and its application based on a corrole fluorophore
Lu, Guifen
Ding, Sihan
Meng, Suci
Zhang, Yiming
DYES AND PIGMENTS, 2024, 227
[19] Dual-response near-infrared fluorescent probe for detecting cyanide and mitochondrial viscosity and its application in bioimaging
Pan, Wei
Han, Linlin
Cao, Xiaoqun
Shen, Shili
Pang, Xianhong
Zhu, Yan
FOOD CHEMISTRY, 2023, 407
[20] A novel near-infrared fluorescent probe with large stokes shifts for sensing extreme acidity and its application in bioimaging
Gong, Jin
Liu, Chang
Jiao, Xiaojie
He, Song
Zhao, Liancheng
Zeng, Xianshun
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2020, 243 (243)

← 1 2 3 4 5 →