Using Drosophila as a model insect

被引：81
|
作者：
Schneider, D [1 ]
机构：
[1] Whitehead Inst, Cambridge Ctr 9, Cambridge, MA 02142 USA
来源：
NATURE REVIEWS GENETICS | 2000年 / 1卷 / 03期
关键词：
D O I：
10.1038/35042080
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The fruitfly Drosophila melanogaster has become such a popular model organism for studying human disease that it is often described as a little person with wings. This view has been strengthened with the sequencing of the Drosophila genome and the discovery that 60% of human disease genes have homologues in the fruitfly. In this review, I discuss the approach of using Drosophila not only as a model for metazoans in general but as a model insect in particular. Specifically, I discuss recent work on the use of Drosophila to study the transmission of disease by insect vectors and to investigate insecticide function and development.
引用
收藏
页码：218 / 226
页数：9
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