Osteoclast-like Giant Cell Tumor of the Parotid Gland Accompanied with Carcinoma ex Pleomorphic Adenoma

被引：2

作者：

Kwon, Mi Jung ^{[2
]}

Nam, Eun Sook ^{[1
]}

Cho, Seong Jin ^{[1
]}

Shin, Hyung Sik ^{[1
]}

Kwon, Ji Hyun ^{[1
]}

Rho, Young Soo ^{[3
]}

机构：

[1] Hallym Univ, Coll Med, Kangdong Sacred Heart Hosp, Dept Pathol, Seoul 134701, South Korea

[2] Hallym Univ, Coll Med, Sacred Heart Hosp, Dept Pathol, Anyang, South Korea

[3] Hallym Univ, Coll Med,Head & Neck Canc Ctr, Kangdong Sacred Heart Hosp,Ilsong Mem Inst, Dept Otorhinolaryngol Head & Neck Surg, Seoul 134701, South Korea

来源：

KOREAN JOURNAL OF PATHOLOGY | 2011年 / 45卷

关键词：

Giant cell tumor; Parotid gland; Mixed tumor; malignant; Osteoclasts; Monocytes; MALIGNANT MIXED TUMOR; SALIVARY-GLAND; BONE; DIAGNOSIS; NEOPLASMS; PANCREAS;

D O I：

10.4132/KoreanJPathol.2011.45.S1.S84

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The origin of osteoclast-like giant cell tumor (OGCT) of the salivary gland has been debated because the prototypic cells of osteoclast-like cells and mononuclear stromal cells are largely unexplained in this gland. Bone marrow-derived CD14+ and CD45+ monocyte-derived multipotential cells (CD14+/CD45+ MOMC) may be one of the possible origins of OGCTs of salivary glands, which have never been explored in salivary OGCTs. We present a case of OGCT accompanied with carcinoma ex pleomorphic adenoma in the parotid gland of a 67-year-old Korean female. The tumor presented as a rapidly growing cervical mass comprising a central area of carcinoma ex pleomorphic adenoma and a peripheral circumferential area of OGCT. The immunohistochemical staining pattern was phenotypically consistent with bone marrow-derived CD14+/CD45+ MOMC. This case is the first report of a salivary OGCT in Korea.

引用

页码：S84 / S88

页数：5

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