Clever Leukemic Stem Cells Branch Out

被引：6
|
作者：
Vyas, Paresh [1 ,3 ]
Jacobsen, Sten Eirik W. [1 ,2 ]
机构：
[1] Univ Oxford, MRC Mol Haematol Unit, Oxford OX3 9DU, England
[2] Univ Oxford, Haematopoiet Stem Cell Lab, Oxford OX3 9DU, England
[3] Univ Oxford, Weatherall Inst Mol Med, Oxford OX3 9DU, England
来源：
CELL STEM CELL | 2011年 / 8卷 / 03期
基金：
英国医学研究理事会;
关键词：
ACUTE LYMPHOBLASTIC-LEUKEMIA; CANCER;
D O I：
10.1016/j.stem.2011.02.015
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Individual tumors harbor heterogeneous populations of genetically distinct subclones. Two recent papers in Nature by Notta et al. (2011) and Anderson et al. (2011) reveal genetic heterogeneity in functional leukemic stem cells, which has important implications for how both cancer and normal stem cell populations may adapt to selective pressure.
引用
收藏
页码：242 / 244
页数：3
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