Green synthesis of cobalt and iron incorporated citric acid/β-cyclodextrin composites: Efficient H2O2 scavengers

Sonochemical procedure was used to synthesize Co/beta-cyclodextrin complex. For the first time, Fe/beta-cyclodextrin complex was also synthesized in alkaline media. Moreover, beta-cyclodextrin was modified by citric acid (CA) and reacted with metal salts under ultrasonic irradiation. The prepared catalysts were characterized by using EDX, UV-vis and FTIR analytical techniques. The highest incorporation of metal into beta-cyclodextrin was observed in the citric acid cross linked beta-CD. The catalase like activity (peroxide scavenging) of Co/beta-CD and Fe/beta-CD complexes and composites was evaluated by UV-visible spectrophotometer and their superoxide scavenging capacity were measured using the pyrogallol method. The Co-3/CA-beta-CD complex showed the best catalase mimetic activity (93.2%) even in comparison to catalase enzyme extracted from potato. Therefore, cobalt complexes of citric acid/beta-CD are promising candidates for H2O2 scavenging. By contrast Fe-3/CA-beta CD complex had stronger capability to eliminate superoxide anion radicals.