Preclinical analysis of the novel Hsp90 inhibitor NVP-HSP990 in multiple myeloma cells

被引:0
|
作者
Stuehmer, T. [1 ]
Iskandarov, K. [1 ]
Nick, H. [2 ]
Einsele, H. [1 ]
Chatterjee, M. [1 ]
Bargou, R. C. [1 ]
机构
[1] Univ Hosp Wurzburg, Dept Internal Med 2, Comprehens Canc Ctr Mainfranken, Wurzburg, Germany
[2] Novartis Inst BioMed Res, Basel, Switzerland
来源
ONKOLOGIE | 2011年 / 34卷
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:160 / 160
页数:1
相关论文
共 50 条
  • [41] Histologic and functional analysis of heat shock protein-90 (HSP90) in multiple myeloma
    Duus, J
    Venkataraman, G
    Bahar, HI
    Izban, KF
    Al-Masri, H
    Maududi, T
    Toor, A
    Alkan, S
    LABORATORY INVESTIGATION, 2006, 86 : 223A - 223A
  • [42] Heat-shock protein (Hsp) 70 inhibition enhances the effect of the Hsp90 inhibitor NVP-AUY922 on melanoma cells
    Yeramian, A.
    Vea, A.
    Santacana, M.
    Matias-Guiu, X.
    Marti, R. M.
    BRITISH JOURNAL OF DERMATOLOGY, 2014, 171 (03) : E48 - E48
  • [43] Heat-shock protein (Hsp)70 inhibition enhances the effect of the Hsp90 inhibitor NVP-AUY922 on melanoma cells
    Yeramian, A.
    Vea, A.
    Santacana, M.
    Matias-Guiu, X.
    Marti, R. M.
    BRITISH JOURNAL OF DERMATOLOGY, 2014, 171 : 36 - 36
  • [44] Repositioning Irsogladine to Hsp90 Inhibitor
    Seo, Young Ho
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2015, 36 (05): : 1495 - 1499
  • [45] NVP-AUY922, a novel HSP90 inhibitor, inhibits the progression of malignant pheochromocytoma in vitro and in vivo
    Lian, Jianpo
    Lin, Dengqiang
    Xie, Xing
    Xu, Yunze
    Xu, Lieyu
    Meng, Li
    Zhu, Yu
    ONCOTARGETS AND THERAPY, 2017, 10 : 2219 - 2226
  • [46] Targeting HSP90 by the Novel Inhibitor NVP-AUY922 Reduces Growth and Angiogenesis of Pancreatic Cancer
    Moser, Christian
    Lang, Sven A.
    Hackl, Christina
    Wagner, Christine
    Scheiffert, Eva
    Schlitt, Hans J.
    Geissler, Edward K.
    Stoeltzing, Oliver
    ANTICANCER RESEARCH, 2012, 32 (07) : 2551 - 2561
  • [47] NVP-AUY922:: A novel small molecule HSP90 inhibitor with potent in vivo antitumor efficacy
    Jensen, Michael Rugaard
    Schoepfer, Joseph
    Radimersky, Thomas
    Massey, Andrew
    Brueggen, Josef
    Schweitzer, Alain
    Pfaar, Ulrike
    Ruetz, Stephan
    Guy, Chantal
    Buckler, Alan
    Schnell, Christian
    Cozens, Robert
    Brough, Paul
    Drysdale, Martin
    Quadt, Cornelia
    Garcia-Echeverria, Carlos
    Chene, Patrick
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3521S - 3521S
  • [48] Cassette dosing in tumor bearing animals for the discovery of NVP-AUY922, a novel HSP90 inhibitor
    Raynaud, Florence I.
    Hayes, Angela
    Martins, Vanessa
    Smith, Nicola F.
    Sharp, Swee Y.
    Valenti, Melanie
    Henley, Alan
    Matthews, Thomas P.
    Cheung, Kwai-Ming
    Kalusa, Andrew
    Jones, Keith
    James, Karen
    McDonald, Edward
    Brough, Paul A.
    Massey, Andrew
    Dymock, Brian
    Drysdale, Martin
    Eccles, Suzanne A.
    Workman, Paul
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3524S - 3524S
  • [49] Activity of new heat shock protein 90 (hsp90) inhibitor NVP-AUY922 against myeloma cells sensitive and resistant to conventional agents
    McMillin, Douglas W.
    Negri, Joseph
    Delmore, Jake
    Hayden, Patrick
    Ooi, Melissa
    Mitsiades, Nicholas
    Schlossman', Robert
    Richardson, Paul G.
    Munshi, Nikhil C.
    Jensen, Michael R.
    Quadt, Cornelia
    Chene, Patrick
    Schoepfer, Joseph
    Garcia-Echeverria, Carlos
    Anderson, Kenneth C.
    Mitsiades, Constantine S.
    BLOOD, 2007, 110 (11) : 474A - 474A
  • [50] NVP-AUY922:: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models
    Jensen, Michael Rugaard
    Schoepfer, Joseph
    Radimerski, Thomas
    Massey, Andrew
    Guy, Chantale T.
    Brueggen, Josef
    Quadt, Cornelia
    Buckler, Alan
    Cozens, Robert
    Drysdale, Martin J.
    Garcia-Echeverria, Carlos
    Chene, Patrick
    BREAST CANCER RESEARCH, 2008, 10 (02)