Arsenic Trioxide Suppresses Growth of BCR-ABL1 Positive Cells with "Gatekeeper" or Compound Mutation

被引：0
|
作者：
Mian, Afsar Ali [1 ]
Raees, Hadiqa [1 ]
Ahmad, Sujjawal [1 ]
Ottmann, Oliver [2 ]
Lalani, El-Nasir M. A. [1 ]
机构：
[1] Aga Khan Univ, Ctr Regenerat Med & Stem Cell Res, Karachi, Pakistan
[2] Cardiff Univ, Sch Med, Div Canc & Genet, Dept Haematol, Cardiff, Wales
来源：
BLOOD | 2021年 / 138卷
关键词：
D O I：
10.1182/blood-2021-154511
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
4346
引用
收藏
页数：3
相关论文
共 50 条
  • [31] BCR-ABL1 COMPOUND MUTANTS DISPLAY DIFFERENTIAL AND DOSE-DEPENDENT RESPONSES TO PONATINIB
    Byrgazov, K.
    Lucini, C.
    Printz, D.
    Koenig, M.
    Valent, P.
    Hantschel, O.
    Lion, T.
    HAEMATOLOGICA, 2017, 102 : 233 - 233
  • [32] Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
    Notta, Faiyaz
    Mullighan, Charles G.
    Wang, Jean C. Y.
    Poeppl, Armando
    Doulatov, Sergei
    Phillips, Letha A.
    Ma, Jing
    Minden, Mark D.
    Downing, James R.
    Dick, John E.
    NATURE, 2011, 469 (7330) : 362 - +
  • [33] A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia
    Vinhas, Raquel
    Lourenco, Alexandra
    Santos, Susana
    Lemos, Marcos
    Ribeiro, Patricia
    de Sousa, Aida Botelho
    Baptista, Pedro Viana
    Fernandes, Alexandra Ramos
    ONCOTARGETS AND THERAPY, 2018, 11 : 8589 - 8598
  • [34] Dynamic Evolution of Ponatinib Resistant BCR-ABL1 T315 and Compound Mutations
    Chen, Jiaqi
    Liu, Hongxing
    Wang, Fang
    Zhang, Yang
    Chen, Xue
    Nie, Daijing
    Li, Yu
    Tan, Yincheng
    Xu, Yuanli
    Ma, Xiaoli
    BLOOD, 2019, 134
  • [35] BCR-ABL1 compound mutants display differential and dose-dependent responses to ponatinib
    Byrgazov, Konstantin
    Lucini, Chantal Blanche
    Valent, Peter
    Hantschel, Oliver
    Lion, Thomas
    HAEMATOLOGICA, 2018, 103 (01)
  • [36] Acquisition Of Compound BCR-ABL1 Alleles As A Mechanism Of Resistance To Ponatinib In Chronic Myeloid Leukemia
    Gibbons, Don L.
    Pricl, Sabrina
    Posocco, Paola
    Laurini, Erik
    Fermeglia, Maurizio
    Talpaz, Moshe
    Cortes, Jorge E.
    Donato, Nicholas J.
    Quintas-Cardama, Alfonso
    BLOOD, 2013, 122 (21)
  • [37] Overcoming clinical BCR-ABL1 compound mutant resistance with combined ponatinib and asciminib therapy
    Eide, Christopher A.
    Brewer, Diana
    Xie, Tao
    Schultz, Anna Reister
    Savage, Samantha L.
    Muratcioglu, Serena
    Merz, Noah
    Press, Richard D.
    O'Hare, Thomas
    Jacob, Thomas
    Vu, Tania Q.
    Tognon, Cristina E.
    Macey, Tara A.
    Kuriyan, John
    Kalodimos, Charalampos G.
    Druker, Brian J.
    CANCER CELL, 2024, 42 (09) : 1486 - 1488
  • [38] Paper or plastic? BCR-ABL1 quantitation and mutation detection from dried blood spots
    Sala Torra, Olga
    Beppu, Lan
    Smith, Jordan L.
    Welden, Linda
    Georgievski, Jasmina
    Gupta, Karisma
    Kumar, Rashmi
    Yeung, Cecilia C. S.
    Paguirigan, Amy
    Gooley, Ted A.
    Branford, Susan
    Radich, Jerald P.
    BLOOD, 2016, 127 (22) : 2773 - +
  • [39] Inhibition of eIF4B suppresses the growth and induces the apoptosis of Bcr-Abl positive cells
    Chen, Ke
    Yang, Jian-Ling
    Guo, Guijie
    Chen, Jilong
    CANCER RESEARCH, 2015, 75
  • [40] ImatinibDrug resistance due to 35 nucleotides BCR-ABL1 insertion mutation: case report
    Reactions Weekly, 2015, 1555 (1) : 104 - 104
12345