Evaluating the effects of chronic MDMA abuses on cerebral metabolism using proton magnetic resonance spectroscopy (1H-MRS)

被引：0
|
作者：
Liu, Wei-Yin
Chen, Po-Chou
Chang, Chen
Chu, Woei-Chyn
机构：
来源：
2008 INTERNATIONAL SPECIAL TOPIC CONFERENCE ON INFORMATION TECHNOLOGY AND APPLICATIONS IN BIOMEDICINE, VOLS 1 AND 2 | 2008年
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中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
MDMA is a widely abused amphetamine derivative that alters serotonin (5-HT) release via the reverse serotonin re-uptake transporter (SERT) mechanism. This phenomenon leads to neurotoxicity in the synaptic clefts, especially in the striatum. As the major function of the striatum is planning and modulating movement pathways and cognitive processes, the objective of this study is to investigate the neuronal viability of chronic MDMA-influenced rats, as well as the effect of re-challenged MDMA.
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页码：213 / 215
页数：3
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