The immunomodulatory (IM) signature enhances prediction of pathologic complete response (pCR) to neoadjuvant therapy (NAT) in triple negative breast cancers (TNBC) with moderate stromal tumour infiltrating lymphocytes (sTIL)

被引：0

作者：

Abuhadra, N. ^{[1
]}

Sun, R. ^{[2
]}

Litton, J. K. ^{[1
]}

Rauch, G. ^{[3
]}

Thompson, A. M. ^{[4
]}

Lim, B. ^{[1
]}

Adrada, B. ^{[3
]}

Mittendorf, E. ^{[5
]}

Damodaran, S. ^{[6
]}

Pitpitan, R. ^{[3
]}

Arun, B. ^{[7
]}

White, J. ^{[1
]}

Ravenberg, E. ^{[1
]}

Santiago, L. ^{[3
]}

Sahin, A. ^{[8
]}

Murthy, R. ^{[6
]}

Ueno, N. T. ^{[1
]}

Ibrahim, N. ^{[1
]}

Moulder, S. ^{[1
]}

Huo, L. ^{[8
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USA

[2] MD Anderson Canc Ctr, Dept Biostat, Houston, TX USA

[3] Univ Texas MD Anderson Canc Ctr, Div Diagnost Imaging, Dept Diagnost Radiol, Houston, TX 77030 USA

[4] Baylor Coll Med, Breast Surg Oncol, Houston, TX 77030 USA

[5] Brigham & Womens Hosp, Surg, 75 Francis St, Boston, MA 02115 USA

[6] MD Anderson Canc Ctr, Breast Med Oncol, Houston, TX USA

[7] MD Anderson Canc Ctr, Breast Med Oncol & Clin Canc Genet, Houston, TX USA

[8] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA

来源：

ANNALS OF ONCOLOGY | 2020年 / 31卷

关键词：

D O I：

10.1016/j.annonc.2020.03.038

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

98O

引用

页码：S49 / S49

页数：1

共 35 条

[31] Predictive Roles of Baseline Stromal Tumor-Infiltrating Lymphocytes and Ki-67 in Pathologic Complete Response in an Early-Stage Triple-Negative Breast Cancer Prospective Trial
Abuhadra, Nour
Sun, Ryan
Yam, Clinton
Rauch, Gaiane M.
Ding, Qingqing
Lim, Bora
Thompson, Alastair M.
Mittendorf, Elizabeth A.
Adrada, Beatriz E.
Damodaran, Senthil
Virani, Kiran
White, Jason
Ravenberg, Elizabeth
Sun, Jia
Choi, Jaihee
Candelaria, Rosalind
Arun, Banu
Ueno, Naoto T.
Santiago, Lumarie
Saleem, Sadia
Abouharb, Sausan
Murthy, Rashmi K.
Ibrahim, Nuhad
Sahin, Aysegul
Valero, Vicente
Symmans, William Fraser
Litton, Jennifer K.
Tripathy, Debu
Moulder, Stacy
Huo, Lei
CANCERS, 2023, 15 (13)
[32] Evaluation of stromal tumor-infiltrating lymphocytes (sTIL) and tertiary lymphoid structures (TLS) in early breast cancer patients with triple negative breast cancer(TNBC) included in a prospective study of neoadjuvant chemotherapy (NAC) with Epirubicin and cyclophosphamide (EC) and carboplatin-paclitaxel (PC) (BSMO 2014-01)
Fontaine, C.
Van den Eynden, G.
de Wind, R.
Boisson, A.
Renard, V.
Van den Bulck, H.
Vuylsteke, P.
Glorieux, P.
Dopchie, C.
Decoster, L.
De Greve, J.
Awada, A.
Wildiers, H.
Willard-Gallo, K.
CANCER RESEARCH, 2019, 79 (04)
[33] Impact of the addition of carboplatin (Cb) and/or bevacizumab (B) to neoadjuvant weekly paclitaxel (P) followed by dose-dense AC on pathologic complete response (pCR) rates in triple-negative breast cancer (TNBC): CALGB 40603 (Alliance)
Sikov, W. M.
Berry, D. A.
Perou, C. M.
Singh, B.
Cirrincione, C.
Tolaney, S.
Kuzma, C. S.
Pluard, T. J.
Somlo, G.
Port, E.
Golshan, M.
Bellon, J. R.
Collyar, D.
Hahn, O. M.
Carey, L. A.
Hudis, C.
Winer, E. P.
CANCER RESEARCH, 2013, 73
[34] Association between stromal tumor-infiltrating lymphocytes (TILs) and pathologic complete response (pCR) in patients with early breast cancer (BC) treated with neoadjuvant chemotherapy and HER2-directed therapies in NSABP B-41.
Schlam, Ilana
Tang, Gong
Harris, Brent T.
Rastogi, Priya
Wolmark, Norman
Salgado, Roberto
Swain, Sandra M.
JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
[35] Impact of intrinsic subtype by PAM50 and other gene signatures on pathologic complete response (pCR) rates in triple-negative breast cancer (TNBC) after neoadjuvant chemotherapy (NACT) plus /- carboplatin (Cb) or bevacizumab (Bev): CALGB 40603/150709 (Allianc
Sikov, William M.
Barry, William T.
Hoadley, Katherine A.
Pitcher, Brandelyn N.
Singh, Baljit
Tolaney, Sara M.
Kuzma, Charles S.
Pluard, Timothy J.
Somlo, George
Port, Elisa R.
Golshan, Mehra
Berry, Donald A.
Hahn, Olwen M.
Carey, Lisa A.
Perou, Charles M.
Hudis, Clifford A.
Winer, Eric P.
CANCER RESEARCH, 2015, 75

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