Chocolate and Coronary Heart Disease: A Systematic Review

被引：27

作者：

Khawaja, Owais ^{[1
,2
,4
]}

Gaziano, J. Michael ^{[1
,2
,3
,4
,5
]}

Djousse, Luc ^{[1
,2
,3
,4
]}

机构：

[1] Brigham & Womens Hosp, Div Aging, OBC, Boston, MA 02120 USA

[2] Harvard Univ, Sch Med, Boston, MA 02120 USA

[3] Boston Vet Affairs Healthcare Syst, Geriatr Res Educ & Clin Ctr GRECC, Boston, MA USA

[4] Boston Vet Affairs Healthcare Syst, Massachusetts Vet Epidemiol & Res Informat Ctr MA, Boston, MA USA

[5] Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02120 USA

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2011年 / 13卷 / 06期

关键词：

Chocolate; Cocoa; Flavanol; Polyphenols; Coronary heart disease; Blood pressure; Epicatechin; Catechin; FLAVANOL-RICH COCOA; DARK CHOCOLATE; BLOOD-PRESSURE; CARDIOVASCULAR HEALTH; ANTIOXIDANT CAPACITY; INSULIN SENSITIVITY; PLATELET-FUNCTION; CONSUMPTION; PREVENTION; MORTALITY;

D O I：

10.1007/s11883-011-0203-2

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Coronary heart disease (CHD) is the leading cause of death in the United States. The high content of polyphenols and flavonoids present in cocoa has been reported to play an important protective role in the development of CHD. Although studies have demonstrated beneficial effects of chocolate on endothelial function, blood pressure, serum lipids, insulin resistance, and platelet function, it is unclear whether chocolate consumption influences the risk of CHD. This article reviews current evidence on the effects of cocoa/chocolate on clinical and subclinical CHD, CHD risk factors, and potential biologic mechanisms. It also discusses major limitations of currently available data and future directions in the field.

引用

页码：447 / 452

页数：6

共 50 条

[1] Chocolate and Coronary Heart Disease: A Systematic Review
Owais Khawaja
J. Michael Gaziano
Luc Djoussé
[J]. Current Atherosclerosis Reports, 2011, 13 : 447 - 452
[2] Coronary heart disease policy models: a systematic review
Unal, Belgin
Capewell, Simon
Critchley, Julia Alison
[J]. BMC PUBLIC HEALTH, 2006, 6 (1)
[3] Ceruloplasmin and Coronary Heart Disease-A Systematic Review
Arenas de Larriva, Antonio P.
Limia-Perez, Laura
Alcala-Diaz, Juan F.
Alonso, Alvaro
Lopez-Miranda, Jose
Delgado-Lista, Javier
[J]. NUTRIENTS, 2020, 12 (10) : 1 - 15
[4] PROTEINURIA AS A PREDICTOR OF CORONARY HEART DISEASE - A SYSTEMATIC REVIEW
Verdon, C.
Perkovic, V.
Ninomiya, T.
Barzi, F.
Craig, J.
Cass, A.
Huxley, R.
[J]. NEPHROLOGY, 2007, 12 : A31 - A31
[5] Coronary heart disease policy models: a systematic review
Belgin Unal
Simon Capewell
Julia Alison Critchley
[J]. BMC Public Health, 6
[6] TONGXINLUO CAPSULE FOR CORONARY HEART DISEASE: A SYSTEMATIC REVIEW
Zhou Zhong-Ran
Tang Hai-Qin
Li Jie-Hua
Yang Lin-Lin
Hu Hao
[J]. HEART, 2010, 96 : A103 - A103
[7] Is coronary heart disease rising in India? A systematic review based on ECG defined coronary heart disease
Ahmad, N
Bhopal, R
[J]. HEART, 2005, 91 (06) : 719 - 725
[8] Chocolate and prevention of cardiovascular disease: A systematic review
Ding, Eric L.
Hutfless, Susan M.
Ding, Xin
Girotra, Saket
[J]. NUTRITION & METABOLISM, 2006, 3 (1)
[9] Chocolate and Prevention of Cardiovascular Disease: A Systematic Review
Eric L Ding
Susan M Hutfless
Xin Ding
Saket Girotra
[J]. Nutrition & Metabolism, 3
[10] Human cytomegalovirus infection and coronary heart disease: a systematic review
Du, Yu
Zhang, Guangxue
Liu, Zhijun
[J]. VIROLOGY JOURNAL, 2018, 15

← 1 2 3 4 5 →