Klebsiella pneumoniae ST258 Producing KPC-3 Identified in Italy Carries Novel Plasmids and OmpK36/OmpK35 Porin Variants

被引：150
|
作者：
Garcia-Fernandez, Aurora [1 ]
Villa, Laura [1 ]
Carta, Claudio [2 ]
Venditti, Carolina [1 ]
Giordano, Alessandra [3 ]
Venditti, Mario [3 ]
Mancini, Carlo [3 ]
Carattoli, Alessandra [1 ]
机构：
[1] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy
[2] Ist Super Sanita, Dept Haematol Oncol & Mol Med, I-00161 Rome, Italy
[3] Univ Roma La Sapienza, Dept Publ Hlth & Infect Dis, Rome, Italy
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2012年 / 56卷 / 04期
关键词：
SPECTRUM-BETA-LACTAMASE; SEQUENCE TYPE 258; CARBAPENEMASE; RESISTANCE; EMERGENCE; GENES;
D O I：
10.1128/AAC.05308-11
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A carbapenemase-resistant Klebsiella pneumoniae strain, clone ST258 producing KPC-3, was fully characterized. The entire plasmid content was investigated, thereby identifying plasmids of the IncFII(k) (two of them similar to pKPQIL and pKPN3, respectively), IncX, and COlE types, carrying a formidable set of resistance genes against toxic compounds, metals, and antimicrobial drugs and a novel iron(III) uptake system.
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收藏
页码：2143 / 2145
页数：3
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