Expanding the Role for Immunotherapy in Triple-Negative Breast Cancer

被引:37
|
作者
Savas, Peter [1 ]
Loi, Sherene [1 ,2 ]
机构
[1] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
[2] Univ Melbourne, Sir Peter MacCallum Dept Oncol, Melbourne, Vic, Australia
关键词
D O I
10.1016/j.ccell.2020.04.007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PD-1 axis blockade, in combination with chemotherapy, improves outcomes in advanced triple-negative breast cancer that is PD-L1 positive. The phase 3 KEYNOTE-522 trial now shows that the addition of pembro-lizumab to chemotherapy improves pathological complete response rates regardless of PD-L1 status and appears to improve survival.
引用
收藏
页码:623 / 624
页数:2
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