Expanding the Role for Immunotherapy in Triple-Negative Breast Cancer

被引:37
|
作者
Savas, Peter [1 ]
Loi, Sherene [1 ,2 ]
机构
[1] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
[2] Univ Melbourne, Sir Peter MacCallum Dept Oncol, Melbourne, Vic, Australia
关键词
D O I
10.1016/j.ccell.2020.04.007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PD-1 axis blockade, in combination with chemotherapy, improves outcomes in advanced triple-negative breast cancer that is PD-L1 positive. The phase 3 KEYNOTE-522 trial now shows that the addition of pembro-lizumab to chemotherapy improves pathological complete response rates regardless of PD-L1 status and appears to improve survival.
引用
收藏
页码:623 / 624
页数:2
相关论文
共 50 条
  • [1] Role of Immunotherapy in Triple-Negative Breast Cancer
    Keenan, Tanya E.
    Tolaney, Sara M.
    [J]. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2020, 18 (04): : 479 - 489
  • [2] The Role of Immunotherapy in Triple-Negative Breast Cancer (TNBC)
    Michaels, Elena
    Chen, Nan
    Nanda, Rita
    [J]. CLINICAL BREAST CANCER, 2024, 24 (04) : 263 - 270
  • [3] Immunotherapy in Triple-Negative Breast Cancer
    Emens, Leisha A.
    [J]. CANCER JOURNAL, 2021, 27 (01): : 59 - 66
  • [4] Immunotherapy in triple-negative breast cancer
    Katz, Heather
    Alsharedi, Mohamed
    [J]. MEDICAL ONCOLOGY, 2018, 35 (01)
  • [5] Immunotherapy for Triple-Negative Breast Cancer
    Cao, Yifeng
    Chen, Chuyang
    Tao, Yi
    Lin, Weifeng
    Wang, Ping
    [J]. PHARMACEUTICS, 2021, 13 (12)
  • [6] Immunotherapy in triple-negative breast cancer
    Heather Katz
    Mohamed Alsharedi
    [J]. Medical Oncology, 2018, 35
  • [7] The Use of Immunotherapy in Triple-Negative Breast Cancer
    Schmid, Peter
    [J]. CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY, 2021, 19 (12) : 770 - 773
  • [8] Advances in immunotherapy for triple-negative breast cancer
    Liu, Yang
    Hu, Yueting
    Xue, Jinqi
    Li, Jingying
    Yi, Jiang
    Bu, Jiawen
    Zhang, Zhenyong
    Qiu, Peng
    Gu, Xi
    [J]. MOLECULAR CANCER, 2023, 22 (01)
  • [9] Advances in immunotherapy for triple-negative breast cancer
    Yang Liu
    Yueting Hu
    Jinqi Xue
    Jingying Li
    Jiang Yi
    Jiawen Bu
    Zhenyong Zhang
    Peng Qiu
    Xi Gu
    [J]. Molecular Cancer, 22
  • [10] Prospects of Immunotherapy for Triple-Negative Breast Cancer
    Qiu, Dan
    Zhang, Guijuan
    Yan, Xianxin
    Xiao, Xinqin
    Ma, Xinyi
    Lin, Shujun
    Wu, Jieyan
    Li, Xinyuan
    Wang, Wandi
    Liu, Junchen
    Ma, Yi
    Ma, Min
    [J]. FRONTIERS IN ONCOLOGY, 2022, 11