Imbalance of growth factor signalling in diabetic kidney disease: is connective tissue growth factor (CTGF, CCN2) the perfect intervention point?

被引:45
|
作者
van Nieuwenhoven, FA
Jensen, LJN
Flyvbjerg, A
Goldschmeding, R
机构
[1] Univ Utrecht, Med Ctr, Dept Pathol, NL-3584 CX Utrecht, Netherlands
[2] Aarhus Univ Hosp, Inst Clin, Med Dept Diabet & Endocrinol, Med Res lABS, DK-8000 Aarhus C, Denmark
关键词
clinical marker; CTGF; diabetes; nephropathy; therapy;
D O I
10.1093/ndt/gfh570
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
引用
收藏
页码:6 / 10
页数:5
相关论文
共 50 条
  • [21] CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes
    Fujisawa, T.
    Hattori, T.
    Ono, M.
    Uehara, J.
    Kubota, S.
    Kuboki, T.
    Takigawa, M.
    OSTEOARTHRITIS AND CARTILAGE, 2008, 16 (07) : 787 - 795
  • [22] Effects of connective tissue growth factor (CTGF/CCN2) on condylar chondrocyte proliferation, migration, maturation, differentiation and signalling pathway
    Xing, Xin
    Li, Zhi
    Yu, Zili
    Cheng, Gu
    Li, Dianqi
    Li, Zubing
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 495 (01) : 1447 - 1453
  • [23] Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer
    Shimo, Tsuyoshi
    Kubota, Satoshi
    Yoshioka, Norie
    Ibaragi, Soichiro
    Isowa, Sachiko
    Eguchi, Takanori
    Sasaki, Akira
    Takigawa, Masaharu
    JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 (07) : 1045 - 1059
  • [24] Connective tissue growth factor (CTGF/CCN2): diagnostic and prognostic value in acute heart failure
    Michael Behnes
    Martina Brueckmann
    Siegfried Lang
    Christel Weiß
    Parviz Ahmad-Nejad
    Michael Neumaier
    Martin Borggrefe
    Ursula Hoffmann
    Clinical Research in Cardiology, 2014, 103 : 107 - 116
  • [25] Development of Normal and Cleft Palate: A Central Role for Connective Tissue Growth Factor (CTGF)/CCN2
    Tarr, Joseph T.
    Lambi, Alex G.
    Bradley, James P.
    Barbe, Mary F.
    Popoff, Steven N.
    JOURNAL OF DEVELOPMENTAL BIOLOGY, 2018, 6 (03):
  • [26] Inhibition of connective tissue growth factor (CTGF/CCN2) in gallbladder cancer cells leads to decreased growth in vitro
    Garcia, Patricia
    Leal, Pamela
    Ili, Carmen
    Brebi, Priscilla
    Alvarez, Hector
    Roa, Juan C.
    INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 2013, 94 (03) : 195 - 202
  • [27] Expression of connective tissue growth factor (CTGF/CCN2) in head and neck squamous cell carcinoma
    Mullis, T. C.
    Tang, X.
    Chong, K. T.
    JOURNAL OF CLINICAL PATHOLOGY, 2008, 61 (05) : 606 - 610
  • [28] Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals
    Brigstock, David R.
    JOURNAL OF CELL COMMUNICATION AND SIGNALING, 2010, 4 (01) : 1 - 4
  • [29] Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals
    David R. Brigstock
    Journal of Cell Communication and Signaling, 2010, 4 : 1 - 4
  • [30] Connective tissue growth factor (CTGF/CCN2): diagnostic and prognostic value in acute heart failure
    Behnes, Michael
    Brueckmann, Martina
    Lang, Siegfried
    Weiss, Christel
    Ahmad-Nejad, Parviz
    Neumaier, Michael
    Borggrefe, Martin
    Hoffmann, Ursula
    CLINICAL RESEARCH IN CARDIOLOGY, 2014, 103 (02) : 107 - 116