Synthesis and evaluation of new cathepsin D inhibitors containing substituted hydroxyethyl piperazine isosteres

被引：0
|
作者：
Velusamy, Priya [1 ]
Driver, Darryl [1 ]
Godwin, Walter E. [2 ]
McConnell, Rose M. [1 ]
机构：
[1] Western Illinois Univ, Dept Chem, Macomb, IL 61455 USA
[2] Univ AR Monticello, Monticello, AR 71657 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 233卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
327-MEDI
引用
收藏
页码：528 / 528
页数：1
相关论文
共 50 条
  • [41] Screening and kinetic studies of new cathepsin D inhibitors
    Sheppard, Donald R.
    Wen, Lisa
    Huang, Jenq-Kuen
    McConnell, Rose M.
    FASEB JOURNAL, 2012, 26
  • [42] Synthesis of New Piperazine Substituted Chalcone Sulphonamides as Antibacterial Agents
    Tang, Yan-Ling
    Li, Yong-Kun
    Li, Min-Xin
    Gao, Hui
    Yang, Xiao-Bi
    Mao, Ze-Wei
    CURRENT ORGANIC SYNTHESIS, 2020, 17 (02) : 136 - 143
  • [43] Synthesis and Biological Evaluation of Novel Piperazine Containing Hydrazone Derivatives
    Kaya, Betul
    Ozkay, Yusuf
    Temel, Halide Edip
    Kaplancikli, Zafer Asim
    JOURNAL OF CHEMISTRY, 2016, 2016
  • [44] Synthesis and antimicrobial evaluation of new chalcones containing piperazine or 2,5-dichlorothiophene moiety
    Tomar, V.
    Bhattacharjee, G.
    Kamaluddin
    Kumar, Ashok
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (19) : 5321 - 5324
  • [45] Synthesis and characterization of new organosoluble metal-free and metallophthalocyanines substituted by four macrocycles containing piperazine moiety
    Gok, Halil Zeki
    Gok, Yasar
    INORGANIC CHEMISTRY COMMUNICATIONS, 2014, 40 : 164 - 167
  • [46] Synthesis and Biological Evaluation of Novel Substituted Chalcone-piperazine Derivatives
    Gao, Hui
    Zheng, Xi
    Zhu, Ping
    Wang, Si
    Wan, Chunping
    Rao, Gaoxiong
    Mao, Zewei
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 38 (03) : 684 - 691
  • [47] Design, Synthetis and Biological Evaluation of Fluorinated Cathepsin D Inhibitors
    Terzani, Francesco
    Salah, Khoubaib Ben Haj
    Guitot, Karine
    Monasson, Olivier
    Zanato, Chiara
    Leroy-Dudal, Johanne
    Kaffy, Julia
    Chelain, Evelyne
    Pytkowicz, Julien
    JOURNAL OF PEPTIDE SCIENCE, 2022, 28
  • [48] Synthesis and in vitro evaluation of new derivatives of 2-substituted-6-fluorobenzo[d]thiazoles as cholinesterase inhibitors
    Imramovsky, Ales
    Pejchal, Vladimir
    Stepankova, Sarka
    Vorcakova, Katarina
    Jampilek, Josef
    Vanco, Jan
    Simunek, Petr
    Kralovec, Karel
    Bruckova, Lenka
    Mandikova, Jana
    Trejtnar, Frantisek
    BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (07) : 1735 - 1748
  • [49] Synthesis of organoselenium compounds for later evaluation as cysteine cathepsin inhibitors
    Karcnik, Jacques
    Andrade, Leandro H.
    Piovan, Leandro
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
  • [50] New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S2 Pocket of Cathepsin B: Design, Synthesis, and Biological Evaluation
    Fustero, Santos
    Rodrigo, Vanessa
    Sanchez-Rosello, Maria
    del Pozo, Carlos
    Timoneda, Joaquin
    Frizler, Maxim
    Sisay, Mihiret T.
    Bajorath, Juergen
    Calle, Luis P.
    Javier Canada, F.
    Jimenez-Barbero, Jesus
    Guetschow, Michael
    CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (19) : 5256 - 5260
12345