SiO2@Fe2O3 core-shell nanoparticles for covalent immobilization and release of sparfloxacin drug

被引：39
|
作者：
El-Gamel, Nadia E. A. [2 ]
Wortmann, Laura [1 ]
Arroub, Karim [1 ]
Mathur, Sanjay [1 ]
机构：
[1] Univ Cologne, Inst Inorgan Chem, D-50939 Cologne, Germany
[2] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 36期
关键词：
TEMPLATE-FREE SYNTHESIS; PARTICLES; HYDROLYSIS; NANORODS; SPHERES;
D O I：
10.1039/c1cc13708e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Silica-coated Fe2O3 nanoparticles were synthesized as carriers for the covalent immobilization and release of antimicrobial drug sparfloxacin (SPFX). SPFX-loaded nanoparticles exhibited time-dependent drug release, with no measurable in vitro cytotoxicity, making the drug@nanoparticle conjugates potentially relevant for nanomedicine applications.
引用
收藏
页码：10076 / 10078
页数：3
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