Structurally simple salicylaldehyde-based fluorescent sensors for amino acids have been obtained by one-step or two-step synthesis. These sensors show significant fluorescence enhancement in the presence of many amino acids at concentrations as low as 10(-5) mol/L. The reversible reaction of the aldehydes with amino acids to form imines in aqueous solution is proposed to account for the observed fluorescence enhancement. (C) 2011 Xi Huai Qiang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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Okayama Univ, Dept Med & Bioengn, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7000082, JapanOkayama Univ, Dept Med & Bioengn, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7000082, Japan
Kitamatsu, Mizuki
Akagi, Kazumasa
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Okayama Univ, Dept Med & Bioengn, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7000082, JapanOkayama Univ, Dept Med & Bioengn, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7000082, Japan
Akagi, Kazumasa
Sisido, Masahiko
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Okayama Univ, Dept Med & Bioengn, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7000082, JapanOkayama Univ, Dept Med & Bioengn, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7000082, Japan