Comparative Effectiveness of Injection Therapies for Hemiplegic Shoulder Pain in Stroke: A Systematic Review and Network Meta-Analysis

被引:15
|
作者
Chiu, Yi-Hsiang [1 ]
Chang, Ke-Vin [1 ,2 ,3 ]
Wu, Wei-Ting [2 ]
Hsu, Po-Cheng [2 ]
Ozcakar, Levent [4 ]
机构
[1] Natl Taiwan Univ, Dept Phys Med & Rehabil, Coll Med, Taipei 10048, Taiwan
[2] Natl Taiwan Univ Hosp, Bei Hu Branch, Dept Phys Med & Rehabil, Taipei 10845, Taiwan
[3] Taipei Med Univ, Wang Fang Hosp, Ctr Reg Anesthesia & Pain Med, Taipei 11600, Taiwan
[4] Hacettepe Univ, Dept Phys & Rehabil Med, Med Sch, TR-06100 Ankara, Turkey
关键词
corticosteroid; hemiplegic shoulder; hyaluronic acid; injection; rehabilitation; TOXIN TYPE-A; SUPRASCAPULAR NERVE BLOCK; BOTULINUM-TOXIN; DOUBLE-BLIND; SPASTIC HEMIPLEGIA; SUBSTANCE-P; SURVIVORS;
D O I
10.3390/ph14080788
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Hemiplegic shoulder pain (HSP) hampers post-stroke functional recovery and is not well managed with conservative treatments. This systematic review aimed to examine the various injection therapies for HSP and investigate their effectiveness at different time points. The protocol of this meta-analysis was registered on INPLASY with a registration number of INPLASY202180010. PubMed, EMBASE, and Scopus were searched from their inception to 4 August 2021 for the clinical studies investigating comparative effectiveness of different injection regimens for treating hemiplegic shoulder pain in patients with stroke. The primary outcome was the weighted mean difference (WMD) on the visual analog scale (VAS) of pain reduction in the fourth-week and between the fourth and twenty-fourth weeks. Ranking probabilities of the WMD for each treatment were obtained using simulations. Seventeen studies with 595 participants were included. The network meta-analysis showed that at the fourth-week, intra-muscular botulinum toxin (BoNT) injections and suprascapular nerve blocks (SSNB) were superior to a placebo, with WMDs of 1.55 (95% CI, 0.09 to 3.01) and 1.44 (95% CI, 0.07 to 2.80), respectively. SSNB possessed the highest probability (53.3%) and appeared to be the best treatment in the fourth-week, followed by intra-muscular BoNT injections (42.6%). Intramuscular BoNT injections were better than the placebo, with a WMD of 1.57 (95% CI, 0.30 to 2.84) between the 4th and 24th weeks. Intramuscular BoNT injections had the highest probability (79.8%) as the best treatment between the 4th and 24th weeks. SSNB was likely to rank first in relieving HSP at the fourth post-treatment week, whereas intra-muscular BoNT injections had the highest probability to achieve the best treatment effectiveness in the post-injection period between the fourth and twenty-fourth weeks. However, as some of the included studies used a non-randomized controlled design, more randomized controlled trials are needed in the future to validate and better understand the short- and long-term efficacy of different injection therapies for management of HSP.
引用
下载
收藏
页数:19
相关论文
共 50 条
  • [1] Effectiveness of Botulinum Toxin A in Treatment of Hemiplegic Shoulder Pain: A Systematic Review and Meta-analysis
    Xie, Hui-Min
    Guo, Ting-Ting
    Sun, Xuan
    Ge, Han-Xiao
    Chen, Xue-Dan
    Zhao, Ke-Jia
    Zhang, Li-Ning
    ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2021, 102 (09): : 1775 - 1787
  • [2] Efficacy of rehabilitative techniques in reducing hemiplegic shoulder pain in stroke: Systematic review and meta-analysis
    de Sire, Alessandro
    Moggio, Lucrezia
    Demeco, Andrea
    Fortunato, Francesco
    Spano, Riccardo
    Aiello, Vincenzo
    Marotta, Nicola
    Ammendolia, Antonio
    ANNALS OF PHYSICAL AND REHABILITATION MEDICINE, 2022, 65 (05)
  • [3] Effectiveness of Suprascapular Nerve Block in the Treatment of Hemiplegic Shoulder Pain: A Systematic Review and Meta-Analysis
    Hou, Yajing
    Wang, Yong
    Sun, Xiaojing
    Lou, Yake
    Yu, Ying
    Zhang, Tong
    FRONTIERS IN NEUROLOGY, 2021, 12
  • [4] Comparative Effectiveness of Therapies for Graves' Hyperthyroidism: A Systematic Review and Network Meta-Analysis
    Sundaresh, Vishnu
    Brito, Juan P.
    Wang, Zhen
    Prokop, Larry J.
    Stan, Marius N.
    Murad, Mohammad H.
    Bahn, Rebecca S.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2013, 98 (09): : 3671 - 3677
  • [5] COMPARATIVE EFFECTIVENESS OF INJECTION THERAPIES IN LATERAL EPICONDYLITIS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
    Krogh, T.
    Bartels, E. M.
    Ellingsen, T.
    Stengaard-Pedersen, K.
    Buchbinder, R.
    Fredberg, U.
    Bliddal, H.
    Christensen, R.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 71 : 77 - 78
  • [6] Comparative Effectiveness of Injection Therapies in Lateral Epicondylitis A Systematic Review and Network Meta-analysis of Randomized Controlled Trials
    Krogh, Thoger Persson
    Bartels, Else Marie
    Ellingsen, Torkell
    Stengaard-Pedersen, Kristian
    Buchbinder, Rachelle
    Fredberg, Ulrich
    Bliddal, Henning
    Christensen, Robin
    AMERICAN JOURNAL OF SPORTS MEDICINE, 2013, 41 (06): : 1435 - 1446
  • [7] Comparative effectiveness of treatment options for subacromial shoulder conditions: a systematic review and network meta-analysis
    Babatunde, Opeyemi O.
    Ensor, Joie
    Littlewood, Chris
    Chesterton, Linda
    Jordan, Joanne L.
    Corp, Nadia
    Wynne-Jones, Gwenllian
    Roddy, Edward
    Foster, Nadine E.
    van der Windt, Danielle A.
    THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021, 13
  • [8] The effectiveness of different acupuncture therapies for neck pain A protocol for systematic review and/or network meta-analysis
    Jo, Hyo-Rim
    Noh, Eun-Ji
    Oh, Se-Hee
    Choi, Seong-Kyeong
    Sung, Won-Suk
    Choi, Su-Ji
    Kim, Dong-Il
    Hong, Seung-Ug
    Kim, Eun-Jung
    MEDICINE, 2021, 100 (16) : E25379
  • [9] Comparative effectiveness of treatments for patellofemoral pain: a living systematic review with network meta-analysis
    Winters, Marinus
    Holden, Sinead
    Lura, Carolina Bryne
    Welton, Nicky J.
    Caldwell, Deborah M.
    Vicenzino, Bill T.
    Weir, Adam
    Rathleff, Michael Skovdal
    BRITISH JOURNAL OF SPORTS MEDICINE, 2021, 55 (07) : 369 - +
  • [10] Comparative effectiveness of different therapies for treating striae distensae A systematic review and network meta-analysis
    Lu, Haishan
    Guo, Jian
    Hong, Xudong
    Chen, Aifen
    Zhang, Xudong
    Shen, Shengxian
    MEDICINE, 2020, 99 (39)