Improved synthesis of γ-nitro-α-amino ester and acid derivatives

被引：8
|
作者：
Ballini, R
Balsamini, C
Bartoccini, F
Gianotti, M
Martinelli, C
Savoretti, N
机构：
[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, MC, Italy
[2] Univ Urbino, Ist Chim Farmaceut, I-61029 Urbino, PU, Italy
来源：
SYNTHESIS-STUTTGART | 2005年 / 02期
关键词：
microwave-assisted synthesis; alpha-amino acids; methyl N-(diphenylmethylene)-2,3-didehydroalaninate; nitroalkanes;
D O I：
10.1055/s-2004-834927
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A useful microwave-assisted synthesis of gamma-nitro-alpha-amino esters and corresponding acids, under mild conditions and without solvent, is described. The desired products were obtained via Michael addition from methyl N-(diphenylmethylene)-2,3-didehydroalaninate and commercially available nitroalkanes.
引用
收藏
页码：296 / 300
页数：5
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