Creating a T cell-inflamed tumor microenvironment overcomes resistance to checkpoint blockade

被引：0
|
作者：
Tang, Haidong [1 ]
Wang, Yang [1 ]
Chlewicki, Lukasz K. [2 ]
Zhang, Yuan [2 ]
Fu, Yang-Xin [1 ,2 ]
机构：
[1] Univ Texas Southwestern Med Ctr, Dallas, TX USA
[2] Univ Chicago, Chicago, IL 60637 USA
来源：
JOURNAL OF IMMUNOLOGY | 2016年 / 196卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [41] The T-cell-inflamed tumor microenvironment as a paradigm for immunotherapy drug development
    Olson, Daniel J.
    Luke, Jason J.
    IMMUNOTHERAPY, 2019, 11 (03) : 155 - 159
  • [42] MACROPHAGE DEPLETION OVERCOMES RESISTANCE TO IMMUNE CHECKPOINT BLOCKADE FOLLOWING IRRADIATION
    Jones, K.
    Tiersma, J.
    Gordon-Weeks, A.
    Yuzhalin, A.
    Muschel, R.
    BRITISH JOURNAL OF SURGERY, 2018, 105 : 45 - 46
  • [43] Inducing Z-DNA overcomes immune checkpoint blockade resistance
    Jiao, Huipeng
    Pasparakis, Manolis
    CELL RESEARCH, 2022, 32 (10) : 871 - 872
  • [44] Inducing Z-DNA overcomes immune checkpoint blockade resistance
    Huipeng Jiao
    Manolis Pasparakis
    Cell Research, 2022, 32 : 871 - 872
  • [45] CAMKK2 PROMOTES AN IMMUNOSUPPRESSIVE PROGRAM AND CHECKPOINT BLOCKADE RESISTANCE IN THE GLIOBLASTOMA TUMOR MICROENVIRONMENT
    Tomaszewski, William
    Waibl-Polania, Jessica
    Racioppi, Luigi
    Sanchez-Perez, Luis
    Michael, Gunn
    Sampson, John
    NEURO-ONCOLOGY, 2021, 23 : 100 - 100
  • [46] TUBA1C orchestrates the immunosuppressive tumor microenvironment and resistance to immune checkpoint blockade in clear cell renal cell carcinoma
    Li, Junyi
    Chen, Meixue
    Tong, Ming
    Cao, Qingfei
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [47] TARGETING HEPATOMA-INTRINSIC PPARγ SIGNALING OVERCOMES IMMUNE CHECKPOINT THERAPY RESISTANCE BY INFLAMING THE TUMOR MICROENVIRONMENT
    Xiong, Zhewen
    Chan, Stephen
    Zhou, Jingying
    Cao, Jianquan
    Vong, Joaquim S. L.
    Zeng, Xuezhen
    Tu, Yalin
    Feng, Yu
    Yip, Kevin
    Sung, Joseph J. Y.
    Cheng, Alfred Sze-Lok
    GUT, 2020, 69 : A25 - A26
  • [48] Resistance to immune checkpoint inhibitors and the tumor microenvironment
    Kawashima, Shusuke
    Togashi, Yosuke
    EXPERIMENTAL DERMATOLOGY, 2023, 32 (03) : 240 - 249
  • [49] A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
    Jerby-Arnon, Livnat
    Shah, Parin
    Cuoco, Michael S.
    Rodman, Christopher
    Su, Mei-Ju
    Melms, Johannes C.
    Leeson, Rachel
    Kanodia, Abhay
    Mei, Shaolin
    Lin, Jia-Ren
    Wang, Shu
    Rabasha, Bokang
    Liu, David
    Zhang, Gao
    Margolais, Claire
    Ashenberg, Orr
    Ott, Patrick A.
    Buchbinder, Elizabeth I.
    Haq, Rizwan
    Hodi, F. Stephen
    Boland, Genevieve M.
    Sullivan, Ryan J.
    Frederick, Dennie T.
    Miao, Benchun
    Moll, Tabea
    Flaherty, Keith T.
    Herlyn, Meenhard
    Jenkins, Russell W.
    Thummalapalli, Rohit
    Kowalczyk, Monika S.
    Canadas, Israel
    Schilling, Bastian
    Cartwright, Adam N. R.
    Luoma, Adrienne M.
    Malu, Shruti
    Hwu, Patrick
    Bernatchez, Chantale
    Forget, Marie-Andree
    Barbie, David A.
    Shalek, Alex K.
    Tirosh, Itay
    Sorger, Peter K.
    Wucherpfennig, Kai
    Van Allen, Eliezer M.
    Schadendorf, Dirk
    Johnson, Bruce E.
    Rotem, Asaf
    Rozenblatt-Rosen, Orit
    Garraway, Levi A.
    Yoon, Charles H.
    CELL, 2018, 175 (04) : 984 - +
  • [50] Effect of STING agonist on tumor immune microenvironment of non-inflamed lung cancer and efficacy of immune checkpoint blockade.
    Chon, Hongjae
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (05)
12345