Hypothalamic/Pituitary Morbidity in Skull Base Pathology

被引:0
|
作者
Lee, Paul [3 ,4 ]
Ho, Ken K. Y. [3 ,4 ,5 ]
Greenfield, Jerry R. [1 ,2 ,6 ,7 ]
机构
[1] Garvan Inst Med Res, Dept Endocrinol, Sydney, NSW 2010, Australia
[2] Ctr Diabet, Sydney, NSW 2010, Australia
[3] Princess Alexandra Hosp, Dept Endocrinol & Diabet, Brisbane, Qld 4102, Australia
[4] Univ Queensland, Sch Med, Brisbane, Qld 4102, Australia
[5] Princess Alexandra Hosp, Ctr Hlth Res, Brisbane, Qld 4102, Australia
[6] Garvan Inst Med Res, Diabet & Obes Program, Sydney, NSW 2010, Australia
[7] Univ New S Wales, Fac Med, Sydney, NSW 2052, Australia
关键词
Hypothalamic dysfunction; Hypopituitarism; Skull base; Craniopharyngioma; GROWTH-HORMONE GH; CHILDHOOD CRANIOPHARYNGIOMA; CONFORMAL RADIOTHERAPY; HYPOPITUITARY PATIENTS; CRANIAL IRRADIATION; PITUITARY; DEFICIENCY; MORTALITY; ADULTS; REPLACEMENT;
D O I
10.1016/j.otc.2011.06.010
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
In this article the epidemiology, pathophysiology, clinical presentation, investigation, management, and prognosis of hypopituitarism and hypothalamic dysfunction, arising from skull base pathologies and treatment of these conditions, are reviewed and discussed. The clinical question: "What is the consequence of pituitary hypofunction in young patients (ie, craniopharyngioma)?" is answered based on information provided in the review.
引用
收藏
页码:1005 / +
页数:18
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