BioImageXD: an open, general-purpose and high-throughput image-processing platform

被引:0
|
作者
Kankaanpaa, Pasi [1 ]
Paavolainen, Lassi [2 ,3 ]
Tiitta, Silja [1 ]
Karjalainen, Mikko [2 ,3 ]
Paivarinne, Joacim [1 ]
Nieminen, Jonna [1 ]
Marjomaki, Varpu [2 ,3 ]
Heino, Jyrki [1 ]
White, Daniel J. [2 ,3 ,4 ]
机构
[1] Univ Turku, Dept Biochem & Food Chem, Turku, Finland
[2] Univ Jyvaskyla, Dept Biol & Environm Sci, Jyvaskyla, Finland
[3] Univ Jyvaskyla, Nanosci Ctr, Jyvaskyla, Finland
[4] Max Planck Inst Mol Cell Biol & Genet, Dresden, Germany
基金
芬兰科学院;
关键词
QUANTITATIVE-ANALYSIS; COLOCALIZATION; VISUALIZATION; MICROSCOPY; INFORMATICS; DOMAIN; TOOLS;
D O I
10.1038/NMETH.2047
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
BioImageXD puts open-source computer science tools for three-dimensional visualization and analysis into the hands of all researchers, through a user-friendly graphical interface tuned to the needs of biologists. BioImageXD has no restrictive licenses or undisclosed algorithms and enables publication of precise, reproducible and modifiable workflows. It allows simple construction of processing pipelines and should enable biologists to perform challenging analyses of complex processes. We demonstrate its performance in a study of integrin clustering in response to selected inhibitors.
引用
收藏
页码:683 / 689
页数:7
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