Oleic Acid Produced by a Marine Vibrio spp. Acts as an Anti-Vibrio parahaemolyticus Agent

被引：13

作者：

Leyton, Yanett ^{[1
]}

Borquez, Jorge ^{[2
]}

Darias, Jose ^{[3
]}

Cueto, Mercedes ^{[3
]}

Diaz-Marrero, Ana R. ^{[3
]}

Riquelme, Carlos ^{[1
]}

机构：

[1] Antofagasta Univ, Fac Marine Resources, Microbial Ecol Lab, Antofagasta 1310000, Chile

[2] Antofagasta Univ, Dept Chem, Lab Nat Prod, Antofagasta 1310000, Chile

[3] CSIC, Inst Nat Prod & Agrobiol, Tenerife 38206, Spain

来源：

MARINE DRUGS | 2011年 / 9卷 / 10期

关键词：

bioactive marine products; inhibition; Vibrio parahaemolyticus; oleic acid; POTENTIAL PROBIOTIC STRAINS; FATTY-ACIDS; RESISTANCE; OUTBREAKS;

D O I：

10.3390/md9102155

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

It is known that some strains of Vibrio parahaemolyticus are responsible for gastroenteric diseases caused by the ingestion of marine organisms contaminated with these bacterial strains. Organic products that show inhibitory activity on the growth of the pathogenic V. parahaemolyticus were extracted from a Vibrio native in the north of Chile. The inhibitory organic products were isolated by reverse phase chromatography and permeation by Sephadex LH20, and were characterized by spectroscopic and spectrometric techniques. The results showed that the prevailing active product is oleic acid, which was compared with standards by gas chromatography and high-performance liquid chromatography (HPLC). These active products might be useful for controlling the proliferation of pathogenic clones of V. parahaemolyticus.

引用

页码：2155 / 2163

页数：9

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