High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals

被引：6
|
作者：
Sum, Samuth [1 ]
Park, Hee-Myung [1 ]
Oh, Jae Young [1 ]
机构：
[1] Konkuk Univ, Dept Vet Internal Med, Coll Vet Med, 120 Neungdong Ro, Seoul 05029, South Korea
来源：
JOURNAL OF VETERINARY SCIENCE | 2020年 / 21卷 / 03期
关键词：
Diseased pets; staphylococci; high-level mupirocin resistance; mupA-IS257; spread; IDENTIFICATION; PREVALENCE; LOCATION; GENE;
D O I：
10.4142/jvs.2020.21.e40
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3 Corynebacterium were high-level mupirocin-resistant (MICs, >= 1,024 ug/mL) harboring mupA. Six staphylococci of HLMR strains had plasmid-mediated mupA-IS257 flanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future.
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页数：8
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