Dynamic decision making requires an intact medial frontal cortex. Recent work has combined theory and single-neuron measurements in frontal cortex to advance models of decision making. We review behavioral tasks that have been used to study dynamic decision making and algorithmic models of these tasks using reinforcement learning theory. We discuss studies linking neurophysiology and quantitative decision variables. We conclude with hypotheses about the role of other cortical and subcortical structures in dynamic decision making, including ascending neuromodulatory systems.
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Washington Univ St Louis, Dept Neurosci, Dept Psychiat, St Louis, MO 63110 USAWashington Univ St Louis, Dept Neurosci, Dept Psychiat, St Louis, MO 63110 USA
Christensen, Amelia J.
Ott, Torben
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Washington Univ St Louis, Dept Neurosci, Dept Psychiat, St Louis, MO 63110 USA
Humboldt Univ, Bernstein Ctr Comp Neurosci Berlin, Berlin, GermanyWashington Univ St Louis, Dept Neurosci, Dept Psychiat, St Louis, MO 63110 USA
Ott, Torben
Kepecs, Adam
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Washington Univ St Louis, Dept Neurosci, Dept Psychiat, St Louis, MO 63110 USAWashington Univ St Louis, Dept Neurosci, Dept Psychiat, St Louis, MO 63110 USA