A randomized controlled trial of analgesia during vaccination in adults

被引:18
|
作者
Taddio, Anna [1 ]
Lord, Allison
Hogan, Mary-Ellen [1 ]
Kikuta, Andrew [1 ]
Yiu, Ashley [1 ]
Darra, Erwin
Bruinse, Barbara [2 ]
Keogh, Tom
Stephens, Derek
机构
[1] Univ Toronto, Leslie Dan Fac Pharmacy, Toronto, ON M5S 3M2, Canada
[2] Hosp Sick Children SickKids, Vasc Access Serv, Toronto, ON M5G 1X8, Canada
关键词
Immunization; Pain management; Adult; ROUTINE CHILDHOOD IMMUNIZATIONS; TOPICAL ANESTHETICS; PAIN MANAGEMENT; INFLUENZA;
D O I
10.1016/j.vaccine.2010.05.015
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Although immunization injections are the most common painful medical procedures, pain-relieving interventions are not routinely used. In this randomized controlled trial, we compared the effectiveness of topical anesthesia using liposomal lidocaine to: (1) vapocoolant spray using a proprietary blend of 1,1,1,3,3-pentafluoropropane and 1,1,1,2-tetrafluoroethane: (2) nurse-administered tactile stimulation; or (3) self-directed distraction by means of reading a magazine. Liposomal lidocaine was more effective (p <= 0.05) than distraction, as assessed by self-reported pain using the visual analog scale and global report, but did not differ from either vapocoolant spray or tactile stimulation. This information can be incorporated in immunization programs. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5365 / 5369
页数:5
相关论文
共 50 条
  • [31] A randomized, controlled trial of immersive virtual reality analgesia, during physical therapy for pediatric burns
    Schmitt, Yuko S.
    Hoffman, Hunter G.
    Blough, David K.
    Patterson, David R.
    Jensen, Mark P.
    Soltani, Maryam
    Carrougher, Gretchen J.
    Nakamura, Dana
    Sharar, Sam R.
    [J]. BURNS, 2011, 37 (01) : 61 - 68
  • [32] COMMENTS ON RANDOMIZED, CONTROLLED TRIAL OF EPIDURAL ANALGESIA IN LABOR - REPLY
    THORP, JA
    HU, DH
    ALBIN, RM
    MEYER, BA
    COHEN, GR
    YEAST, JD
    HEDRICK, J
    MCKENZIE, DR
    GERALD, KB
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1994, 171 (05) : 1401 - 1410
  • [33] Seasonal Influenza Vaccination at School A Randomized Controlled Trial
    Humiston, Sharon G.
    Schaffer, Stanley J.
    Szilagyi, Peter G.
    Long, Christine E.
    Chappel, Tahleah R.
    Blumkin, Aaron K.
    Szydlowski, Jill
    Kolasa, Maureen S.
    [J]. AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2014, 46 (01) : 1 - 9
  • [34] Randomized controlled trial of concurrent hepatitis A and B vaccination
    Bryan, JP
    McCardle, P
    South-Paul, JE
    Fogarty, JP
    Legters, LJ
    Perine, PL
    [J]. MILITARY MEDICINE, 2001, 166 (02) : 95 - 101
  • [35] Preemptive analgesia with tapentadol in inguinal surgery; a randomized controlled trial
    Vadhanan, Prasanna
    Rajendran, Iniya
    Kumar, Vinith
    [J]. ANAESTHESIA PAIN & INTENSIVE CARE, 2023, 27 (03) : 356 - 359
  • [36] Opioid Analgesia for Medical Abortion: A Randomized Controlled Trial Reply
    Colwill, Alyssa C.
    Bayer, Lisa L.
    Bednarek, Paula
    Garg, Bharti
    Jensen, Jeffery T.
    Edelman, Alison B.
    [J]. OBSTETRICS AND GYNECOLOGY, 2020, 135 (06): : 1486 - 1486
  • [37] Postoperative analgesia for pediatric craniotomy patients: a randomized controlled trial
    Fei Xing
    Li Xin An
    Fu Shan Xue
    Chun Mei Zhao
    Ya Fan Bai
    [J]. BMC Anesthesiology, 19
  • [38] Postoperative analgesia for pediatric craniotomy patients: a randomized controlled trial
    Xing, Fei
    An, Li Xin
    Xue, Fu Shan
    Zhao, Chun Mei
    Bai, Ya Fan
    [J]. BMC ANESTHESIOLOGY, 2019, 19 (1)
  • [39] Nefopam as a multimodal analgesia in thoracoscopic surgery: a randomized controlled trial
    Ki, Hyun-Seo
    Shim, Jae-Geum
    Choi, Hyung-Kyeong
    Ryu, Kyoung-Ho
    Kang, Du-Young
    Park, Jiyeon
    Ahn, Jin Hee
    Lee, Sung Hyun
    Cho, Eun-Ah
    [J]. JOURNAL OF THORACIC DISEASE, 2024, 16 (06)
  • [40] Optimizing Mood Prior to Influenza Vaccination in Older Adults: A Three-Arm Randomized Controlled Trial
    Ayling, Kieran
    Brown, Michaela
    Carlisle, Sophie
    Bennett, Robert
    Buchanan, Heather
    Dumbleton, Jennifer
    Hawkey, Christopher
    Hoschler, Katja
    Jack, Ruth H.
    Jonathan, Nguyen-Van-Tam
    Royal, Simon
    Turner, David
    Zambon, Maria
    Fairclough, Lucy
    Vedhara, Kavita
    [J]. HEALTH PSYCHOLOGY, 2024, 43 (02) : 77 - 88