Role of MKK3/P38 Axis in Free Heme Induced Cytokine Storm and Pulmonary Hypertension

被引：0
|
作者：
Varghese, M. Valuparampil [1 ]
James, J. [1 ]
Rafikova, O. [2 ]
Rafikov, R. [1 ]
机构：
[1] Univ Arizona, Dept Med, Tucson, AZ USA
[2] Univ Arizona, Tucson, AZ USA
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2021年 / 203卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A3655
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3 - MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo
    Deacon, K
    Blank, JL
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (22) : 14489 - 14496
  • [32] ENPP1 deletion causes mouse osteoporosis via the MKK3/p38 MAPK/PCNA signaling pathway
    Qiang Wang
    Zhiqiang Gao
    Kai Guo
    Jiawei Lu
    Feng Wang
    Yufeng Huang
    Desheng Wu
    Journal of Orthopaedic Surgery and Research, 17
  • [33] TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase
    Pattison, Michael J.
    Mitchell, Olivia
    Flynn, Helen R.
    Chen, Chao-Sheng
    Yang, Huei-Ting
    Ben-Addi, Hakem
    Boeing, Stefan
    Snijders, Ambrosius P.
    Ley, Steven C.
    BIOCHEMICAL JOURNAL, 2016, 473 : 2845 - 2861
  • [34] Antimycin A induced cardioprotection is dependent on pre-ischemic p38-MAPK activation but independent of MKK3
    Kabir, AMN
    Cao, XB
    Gorog, DA
    Tanno, M
    Bassi, R
    Bellahcene, M
    Quinlan, RA
    Davis, RJ
    Flavell, RA
    Shattock, MJ
    Marber, MS
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2005, 39 (04) : 709 - 717
  • [35] An alternative p38 activation pathway by TAB1 mediates different downstream effects in cardiac myocytes from MKK3
    Lu, G
    Herschman, HR
    Han, JH
    Wang, YB
    CIRCULATION, 2004, 110 (17) : 286 - 286
  • [36] Role of the p38 MAPK pathway in oxidative stress induced expression of heme oxygenase
    Sevak, Shruti
    Stapleton, Susan R.
    IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2007, 43 (07) : 266 - 266
  • [37] miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF
    Pin, Anne-Laure
    Houle, Francois
    Guillonneau, Maeva
    Paquet, Eric R.
    Simard, Martin J.
    Huot, Jacques
    ANGIOGENESIS, 2012, 15 (04) : 593 - 608
  • [38] miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF
    Anne-Laure Pin
    François Houle
    Maëva Guillonneau
    Éric R. Paquet
    Martin J. Simard
    Jacques Huot
    Angiogenesis, 2012, 15 : 593 - 608
  • [39] MiR-21a-5p suppresses bisphenol A-induced pre-adipocyte differentiation by targeting map2k3 through MKK3/p38/MAPK
    Xie, Xiuwen
    Song, Jia
    Li, Gang
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 473 (01) : 140 - 146
  • [40] The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling
    Leonardo Pedrazza
    Taiane Schneider
    Ramon Bartrons
    Francesc Ventura
    Jose Luis Rosa
    Scientific Reports, 10
12345