Reactions of dimethyl and di-tert-butyl 2-aryl-4-hydroxy-4-methyl-6-oxocyclohexane-1,3-dicarboxylates with difunctional nucleophiles

被引：8

作者：

Gein, VL ^{[1
]}

Gein, NV

Potemkin, KD

Kriven'ko, AP

机构：

[1] Perm State Pharmaceut Acad, Perm, Russia

[2] Saratov NG Chernyshevskii State Univ, Saratov, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2004年 / 74卷 / 10期

基金：

俄罗斯基础研究基金会;

关键词：

Ester; Hydrate; Dimethyl; Hydrazine; Alkyl Group;

D O I：

10.1007/s11176-005-0056-x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The nature of the alkyl group in the ester moieties of dimethyl and di-tert-butyl 2-aryl-4-hydroxy-4-methyl-6-oxocyclohexane-1,3-dicarboxylates affects the direction of their reactions with difunctional nucleophiles. The dimethyl esters react with hydrazine hydrate to give the corresponding tetrahydroindazoles, while their tert-butyl analogs are converted under similar conditions into 6-hydrazones. Reactions of both dimethyl and di-tert-butyl 6-oxocyclohexane-1,3-dicarboxylates with hydroxylamine lead to formation of 6-hydroxyimino derivatives.

引用

页码：1564 / 1568

页数：5

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