Crystal Structure of the Trypanosoma cruzi Protein Tyrosine Phosphatase TcPTP1

被引:0
|
作者
Lountos, G. [1 ,2 ]
Tropea, J. [2 ]
Waugh, D. [2 ]
机构
[1] Leidos Biomed Res Inc, Frederick Natl Lab Canc Res, Basic Sci Program, Frederick, MD USA
[2] NCI, Macromol Crystallog Lab, Frederick, MD 21701 USA
关键词
phosphatase; drug target;
D O I
10.1107/S205327331409175X
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
MS53.P22
引用
收藏
页码:C824 / C824
页数:1
相关论文
共 50 条
  • [21] Negative regulation of EGFR signalling through integrin-α1β1-mediated activation of protein tyrosine phosphatase TCPTP
    Mattila, E
    Pellinen, T
    Nevo, J
    Vuoriluoto, K
    Arjonen, A
    Ivaska, J
    NATURE CELL BIOLOGY, 2005, 7 (01) : 78 - +
  • [22] Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase
    Li, SQ
    Depetris, RS
    Barford, D
    Chernoff, J
    Hubbard, SR
    STRUCTURE, 2005, 13 (11) : 1643 - 1651
  • [23] Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone
    Ylilauri, Mikko
    Mattila, Elina
    Nurminen, Elisa M.
    Kapyla, Jarmo
    Niinivehmas, Sanna P.
    Maatta, Juha A.
    Pentikainen, Ulla
    Ivaska, Johanna
    Pentikainen, Olli T.
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2013, 1834 (10): : 1988 - 1997
  • [24] A 1.4 Å crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi
    Focia, PJ
    Craig, SP
    Nieves-Alicea, R
    Fletterick, RJ
    Eakin, AE
    BIOCHEMISTRY, 1998, 37 (43) : 15066 - 15075
  • [25] Diphenylether Derivative as Selective Inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) Over T-cell Protein Tyrosine Phosphatase (TCPTP) Identified through Virtual Screening
    Reddy, M. V. V. V. Sekhar
    Ghadiyaram, Chakshusmathi
    Panigrahi, Sunil Kumar
    Hosahalli, Subramanya
    Mangamoori, Lakshmi Narasu
    MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 13 (11) : 1602 - 1606
  • [26] Negative regulation of EGFR signalling through integrin-α1β1-mediated activation of protein tyrosine phosphatase TCPTP
    Elina Mattila
    Teijo Pellinen
    Jonna Nevo
    Karoliina Vuoriluoto
    Antti Arjonen
    Johanna Ivaska
    Nature Cell Biology, 2005, 7 : 78 - 85
  • [27] Crystal structure of triosephosphate isomerase from Trypanosoma cruzi in hexane
    Gag, XG
    Maldonado, E
    Pérez-Montfort, R
    Garza-Ramos, G
    De Gómez-Puyou, MT
    Gómez-Puyou, A
    Rodríguez-Romero, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (18) : 10062 - 10067
  • [28] Estrogenic regulation of T-cell protein tyrosine phosphatase (TCPTP) in the hypothalamus controlling feeding behavior
    Fukushima, Atsushi
    Funabashi, Toshiya
    Akema, Tatsuo
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, 63 : S284 - S284
  • [29] The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor
    Klingler-Hoffmann, M
    Fodero-Tavoletti, MT
    Mishima, K
    Narita, Y
    Cavenee, WK
    Furnari, FB
    Huang, HJS
    Tiganis, T
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (49) : 46313 - 46318
  • [30] Trypanosoma rangeli protein tyrosine phosphatase is associated with the parasite's flagellum
    Prestes, Elisa Beatriz
    Bayer-Santos, Ethel
    Stoco, Patricia Hermes
    Marques Sincero, Thais Cristine
    Wagner, Glauber
    Umaki, Adriana
    Fragoso, Stenio Perdigao
    Bordignon, Juliano
    Steindel, Mario
    Grisard, Edmundo Carlos
    MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2012, 107 (06): : 713 - U159