Preparation and characterization of inclusion complexes of topotecan with sulfonatocalixarene

被引：50
|
作者：
Wang, Guo-Song [1 ]
Zhang, Heng-Yi [1 ]
Ding, Fei [1 ]
Liu, Yu [1 ]
机构：
[1] Nankai Univ, Dept Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
来源：
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY | 2011年 / 69卷 / 1-2期
关键词：
Sulfonatocalixarenes; Topotecan; Supramolecular chemistry; Inclusion complexation; SALVAGE THERAPY; ONCOLOGY-GROUP; CANCER; SOLUBILIZATION; CYCLODEXTRINS; CARCINOMA;
D O I：
10.1007/s10847-010-9817-1
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Inclusion complex of sulfonatocalix[4]arene (SC4A) with topotecan (TPT) was prepared, and its inclusion complexation behaviors, such as stoichiometry, complex stability constants, and inclusion mode, were investigated by means of UV/Vis spectroscopy, DSC, and 2D NMR. The obtained results show that the quinoline ring and the dimethylaminomethyl group of TPT can be efficiently encapsulated in SC4A, and the complex is more soluble than free TPT.
引用
收藏
页码：85 / 89
页数：5
相关论文
共 50 条
  • [1] Preparation and characterization of inclusion complexes of topotecan with sulfonatocalixarene
    Guo-Song Wang
    Heng-Yi Zhang
    Fei Ding
    Yu Liu
    Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2011, 69 : 85 - 89
  • [2] Preparation and Characterization of Pioglitazone Cyclodextrin Inclusion Complexes
    Pandit, V
    Gorantla, R.
    Devi, K.
    Pai, R. S.
    Sarasija, S.
    JOURNAL OF YOUNG PHARMACISTS, 2011, 3 (04) : 267 - 274
  • [3] Preparation and characterization of inclusion complexes of polyisobutylene with cyclodextrins
    Harada, A
    Suzuki, S
    Okada, M
    Kamachi, M
    MACROMOLECULES, 1996, 29 (17) : 5611 - 5614
  • [4] Preparation and characterization of quercetin and rutin cyclodextrin inclusion complexes
    Vijaya, K.
    Kondaiah, A.
    Ratna, J. Vijaya
    Annapurna, A.
    DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2007, 33 (03) : 245 - 253
  • [5] PREPARATION AND CHARACTERIZATION OF AMYLOSE-PYRAZINAMIDE INCLUSION COMPLEXES
    Ribeiro, C. Andresa
    Fonseca, P. Luis
    Soares, M. D. Rosane
    da Silveira, P. Nadya
    Peres, L. Gisele
    2015 IEEE 4TH PORTUGUESE MEETING ON BIOENGINEERING (ENBENG), 2015,
  • [6] Preparation and characterization of inclusion complexes of aliphatic polyesters with cyclodextrins
    Harada, A
    Nishiyama, T
    Kawaguchi, Y
    Okada, M
    Kamachi, M
    MACROMOLECULES, 1997, 30 (23) : 7115 - 7118
  • [7] Preparation and characterization of [6]-gingerol/β-cyclodextrin inclusion complexes
    da Silva, James Almada
    Sampaio, Pedrita Alves
    Luna Dulcey, Liany Johanna
    Cominetti, Marcia Regina
    Rabello, Marcelo Montenegro
    Rolim, Larissa Araujo
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2021, 61
  • [8] Preparation, Characterization, and Properties of Inclusion Complexes of Balofloxacin with Cyclodextrins
    Ren, Xiuyun
    Qian, Hongyun
    Tang, Peixiao
    Tang, Yuling
    Liu, Yuanyuan
    Pu, Hongyu
    Zhang, Man
    Zhao, Ludan
    Li, Hui
    AAPS PHARMSCITECH, 2019, 20 (07)
  • [9] Preparation and characterization of inclusion complexes of β-cyclodextrin with ionic liquid
    Gao, YA
    Li, ZH
    Du, JM
    Han, BX
    Li, GZ
    Hou, WG
    Shen, D
    Zheng, LQ
    Zhang, GY
    CHEMISTRY-A EUROPEAN JOURNAL, 2005, 11 (20) : 5875 - 5880
  • [10] Preparation and Characterization of Nanoparticle β-Cyclodextrin: Geraniol Inclusion Complexes
    Hadian, Zahra
    Maleki, Majedeh
    Abdi, Khosro
    Atyabi, Fatemeh
    Mohammadi, Abdoreza
    Khaksar, Ramin
    IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2018, 17 (01): : 39 - 51
12345