Chromosomal Aberrations in Cattle

被引：15

作者：

Holeckova, Beata ^{[1
]}

Schwarzbacherova, Viera ^{[1
]}

Galdikova, Martina ^{[1
]}

Kolenicova, Simona ^{[1
]}

Haluskova, Jana ^{[1
]}

Stanicova, Jana ^{[2
,3
]}

Verebova, Valeria ^{[3
]}

Jutkova, Annamaria ^{[1
]}

机构：

[1] Univ Vet Med & Pharm, Dept Biol & Physiol, Komenskeho 73, Kosice 04181, Slovakia

[2] Charles Univ Prague, Fac Med 1, Salmovska 1, Prague 12108, Czech Republic

[3] Univ Vet Med & Pharm, Dept Chem Biochem & Biophys, Komenskeho 73, Kosice 04181, Slovakia

来源：

GENES | 2021年 / 12卷 / 09期

关键词：

chromosomes; aberrations; Robertsonian translocations; reciprocal translocations; genotoxic agents; cattle; WHOLE-GENOME AMPLIFICATION; RECIPROCAL TRANSLOCATION; ROBERTSONIAN TRANSLOCATIONS; BOVINE LYMPHOCYTES; DOMESTIC BOVIDS; DAIRY-CATTLE; DAMAGE; FORMULATION; FREQUENCY; MICRODISSECTION;

D O I：

10.3390/genes12091330

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Chromosomal aberrations and their mechanisms have been studied for many years in livestock. In cattle, chromosomal abnormalities are often associated with serious reproduction-related problems, such as infertility of carriers and early mortality of embryos. In the present work, we review the mechanisms and consequences of the most important bovine chromosomal aberrations: Robertsonian translocations and reciprocal translocations. We also discuss the application of bovine cell cultures in genotoxicity studies.

引用

页数：16

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