THE EFFECT OF GUSELKUMAB ON ENTHESITIS: RESULTS FROM A PHASE 2 STUDY IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS

被引：1
|
作者：
Helliwell, P. [1 ]
Gottlieb, A. B. [2 ]
Deodhar, A. [3 ]
Boehncke, W. -H. [4 ]
McGonagle, D. [1 ]
Xu, X. L. [5 ]
Xu, S. [5 ]
Wang, Y. [5 ]
Hsia, E. C. [5 ,6 ]
Karyekar, C. S. [7 ]
Mease, P. [8 ,9 ]
机构：
[1] Univ Leeds, Leeds, W Yorkshire, England
[2] Metropolitan Hosp, NY Med Coll, New York, NY USA
[3] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
[4] Univ Geneva, Geneva, Switzerland
[5] Janssen Res & Dev LLC, Spring House, PA USA
[6] Univ Penn, Philadelphia, PA USA
[7] Janssen Sci Affairs LLC, Horsham, PA USA
[8] Swedish Med Ctr, Seattle, WA USA
[9] Univ Wash, Seattle, WA USA
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2018年 / 77卷
关键词：
D O I：
10.1136/annrheumdis-2018-eular.5460
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
SAT0344
引用
收藏
页码：1037 / 1037
页数：1
相关论文
共 50 条
  • [11] The Effect of Guselkumab on PASDAS, GRACE Index, mCPDAI and DAPSA: Results from a Phase 2 Study in Patients with Active Psoriatic Arthritis
    Gladman, Dafna
    Helliwell, Philip
    Deodhar, Atul
    Gottlieb, Alice
    Boehncke, Wolf-Henning
    Xu, Lillian
    Xu, Stephen
    Wang, Yuhua
    Hsia, Elizabeth
    Ritchlin, Christopher
    JOURNAL OF RHEUMATOLOGY, 2019, 46 (07) : 848 - 848
  • [12] CONSISTENT EFFICACY IN PATIENT SUBGROUPS ACROSS BASELINE DEMOGRAPHICS AND DISEASE CHARACTERISTICS: RESULTS FROM A PHASE 2 STUDY OF GUSELKUMAB IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS
    McInnes, Iain
    Helliwell, Philip
    Gottlieb, Alice B.
    Boehncke, Wolf-Henning
    Xu, Xie L.
    Xu, Stephen
    Wang, Yuhua
    Hsia, Elizabeth C.
    Deodhar, Atul
    ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 : 1277 - 1278
  • [13] Impact of guselkumab on fatigue and mediation analysis of independent treatment effect of guselkumab on fatigue in patients with active psoriatic arthritis: Results from DISCOVER-1&2
    Rahman, Proton
    Helliwell, Philip S.
    Deodhar, Atul
    Kollmeier, Alexa P.
    Hsia, Elizabeth
    Zhou, Bei
    Lin, Xiwu
    Han, Chenglong
    Yang, Ya-Wen
    Mease, Philip J.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2021, 85 (03) : AB153 - AB153
  • [14] Efficacy of Tofacitinib on Enthesitis in Patients with Active Psoriatic Arthritis
    Mease, Philip
    Orbai, Ana-Maria
    FitzGerald, Oliver
    Bedaiwi, Mohamed
    Fleishaker, Dona L.
    Mundayat, Rajiv
    Young, Pamela
    Helliwell, Philip S.
    ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 3774 - 3776
  • [15] Guselkumab Improves Anemia in Patients with Active Psoriatic Arthritis: Results From Two Phase 3 Randomized Controlled Clinical Trials
    Kavanaugh, Arthur
    Liu, Yang
    Rahman, Proton
    Mease, Philip
    Gossec, Laure
    Xu, Lillian
    Hsia, Elizabeth
    Shawi, May
    Han, Chenglong
    Neuhold, Marlies
    Deodhar, Atul
    JOURNAL OF RHEUMATOLOGY, 2022, 49 (07) : 788 - 789
  • [16] Ixekizumab Treatment Significantly Improves Enthesitis and Dactylitis in Patients with Active Psoriatic Arthritis: Results from Two Phase 3 Trials
    Gladman, Dafna D.
    Orbai, Ana-Maria
    Gallo, Gaia
    Birt, Julie
    Rathmann, Suchitrita
    Marzo-Ortega, Helena
    ARTHRITIS & RHEUMATOLOGY, 2018, 70
  • [17] EFFICACY AND SAFETY RESULTS OF GUSELKUMAB IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS OVER 56 WEEKS
    Boehncke, Wolf Henning
    Gottlieb, Alice
    Deodhar, Atul
    Dong, Bin
    Wang, Yuhua
    Zhuang, Yanli
    Barchuk, William
    Xu, Xie L.
    Hsia, Elizabeth
    ACTA DERMATO-VENEREOLOGICA, 2018, 98 : 48 - 49
  • [18] Ustekinumab Is Superior to TNF Inhibitor Treatment in Resolving Enthesitis in Psa Patients with Active Enthesitis-Results from the Enthesial Clearance in Psoriatic Arthritis Study
    Araujo, Elizabeth G.
    Englbrecht, Matthias
    Hoepken, Sabrina
    Finzel, Stephanie
    Hueber, Axel J.
    Rech, Juergen
    Schett, Georg
    ARTHRITIS & RHEUMATOLOGY, 2017, 69
  • [19] Resolution of enthesitis by guselkumab and relationships to disease burden: 1-year results of two phase 3 psoriatic arthritis studies
    McGonagle, Dennis
    McInnes, Iain B.
    Deodhar, Atul
    Schett, Georg
    Shawi, May
    Kafka, Shelly
    Karyekar, Chetan S.
    Kollmeier, Alexa P.
    Hsia, Elizabeth C.
    Xu, Xie L.
    Sheng, Shihong
    Agarwal, Prasheen
    Zhou, Bei
    Ritchlin, Christopher T.
    Rahman, Proton
    Mease, Philip J.
    RHEUMATOLOGY, 2021, 60 (11) : 5337 - 5350
  • [20] Effect of guselkumab on serum biomarkers in patients with active psoriatic arthritis and inadequate response to tumor necrosis factor inhibitors: results from the COSMOS phase 3b study
    Schett, Georg
    Chen, Warner
    Gao, Sheng
    Chakravarty, Soumya D.
    Shawi, May
    Lavie, Frederic
    Zimmermann, Miriam
    Sharaf, Mohamed
    Coates, Laura C.
    Siebert, Stefan
    ARTHRITIS RESEARCH & THERAPY, 2023, 25 (01)
12345