Biomolecular recognition based on single gold nanoparticle light scattering

被引：639
|
作者：
Raschke, G
Kowarik, S
Franzl, T
Sonnichsen, C
Klar, TA
Feldmann, J
Nichtl, A
Kürzinger, K
机构：
[1] Univ Munich, Dept Phys, Photon & Optoelect Grp, D-80799 Munich, Germany
[2] Univ Munich, CeNS, D-80799 Munich, Germany
[3] Roche Diagnost GmbH, D-82372 Penzberg, Germany
来源：
NANO LETTERS | 2003年 / 3卷 / 07期
关键词：
D O I：
10.1021/nl034223+
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method for biomolecular recognition is reported using light scattering of a single gold nanoparticle functionalized with biotin. Addition of streptavidin and subsequent specific binding events alter the dielectric environment of the nanoparticle, resulting in a spectral shift of the particle plasmon resonance. As we use single nanoparticles showing a homogeneous scattering spectrum, spectral shifts as small as 2 meV can be detected.
引用
收藏
页码：935 / 938
页数：4
相关论文
共 50 条
  • [41] Biomolecular recognition based on localized surface plasmon resonance of immobilized gold nanorods
    Jiang, Li
    Li, Xin
    Zhan, Qiuqiang
    Qian, Jun
    AOE 2008: ASIA OPTICAL FIBER COMMUNICATION AND OPTOELECTRONIC EXPOSITION AND CONFERENCE, 2009,
  • [42] Gold Nanoparticle Coupled with Dynamic Light Scattering for Protein Complex Detection and Analysis
    Huo, Qun
    Jaganathan, Soumya
    Turkson, James
    Yue, Peibin
    BIOPHYSICAL JOURNAL, 2011, 100 (03) : 387 - 387
  • [43] Nanoparticle research based on phase analysis light scattering
    Weiner, B
    McFadyen, P
    AMERICAN LABORATORY, 2002, 34 (11) : 16 - 16
  • [44] A new method of biomolecular recognition of avidin by light scattering of ZnS:Mn nano-particles
    Rabiee, M.
    Mirhabibi, A. R.
    Zadeh, F. Moztar
    Aghababazadeh, R.
    Pour, E. Mohaghegh
    Lin, L.
    PIGMENT & RESIN TECHNOLOGY, 2008, 37 (04) : 224 - 228
  • [45] Biomolecular sensing using gold nanoparticle–coated ZnO nanotetrapods
    Ramakrishna Podila
    Pengyu Chen
    Jason Reppert
    Apparao M. Rao
    Pu Chun Ke
    Journal of Materials Research, 2011, 26 : 2328 - 2333
  • [46] Study of Single Gold Nanocrystals by Inelastic Light Scattering Spectroscopy
    Timm, Mariana M.
    Saviot, Lucien
    Crut, Aurelien
    Blanchard, Nicholas
    Roiban, Lucian
    Masenelli-Varlot, Karine
    Joly-Pottuz, Lucile
    Margueritat, Jeremie
    JOURNAL OF PHYSICAL CHEMISTRY C, 2022, 126 (07): : 3606 - 3613
  • [47] Plasmon scattering from a single gold nanoparticle collected through an optical fiber
    Eah, SK
    Jaeger, HM
    Scherer, NF
    Wiederrecht, GP
    Lin, XM
    APPLIED PHYSICS LETTERS, 2005, 86 (03) : 1 - 3
  • [48] Single gold nanoparticle electrode for electrogenerated chemiluminescence and dark field scattering spectroelectrochemistry
    Wusimanjiang, Yiliyasi
    Ma, Yanxiao
    Lee, Meredith
    Pan, Shanlin
    ELECTROCHIMICA ACTA, 2018, 269 : 291 - 298
  • [49] A biomolecular recognition approach for the functionalization of cellulose with gold nanoparticles
    Almeida, A.
    Rosa, A. M. M.
    Azevedo, A. M.
    Prazeres, D. M. F.
    JOURNAL OF MOLECULAR RECOGNITION, 2017, 30 (09)
  • [50] Plasmonic single nanoparticle for resonance light scattering imaging analysis and applications
    Pan, Zi Yu
    Huang, Cheng Zhi
    Zhan, Lei
    Zhou, Jun
    TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2023, 164
12345