GENOME-WIDE CRISPR-CAS9 SCREEN TO IDENTIFY NEW PROTEINS INVOLVED IN INTRACELLULAR CHOLESTEROL TRANSPORT

被引：0
|
作者：
Meurs, A. [1 ]
De Lint, K. [2 ]
Zelcer, N. [1 ]
机构：
[1] Amsterdam UMC, Locatie AMC, Med Biochem, Amsterdam, Netherlands
[2] Amsterdam UMC, Locatie VUMc, Clin Genet, Amsterdam, Netherlands
来源：
ATHEROSCLEROSIS | 2022年 / 355卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
SE027
引用
收藏
页码：E41 / E41
页数：1
相关论文
共 50 条
  • [41] Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells
    Wang, Yicun
    Wu, Jinhui
    Chen, Hui
    Yang, Yang
    Xiao, Chengwu
    Yi, Xiaoming
    Shi, Changjie
    Zhong, Ke
    He, Haowei
    Li, Yaoming
    Wu, Zhenjie
    Zhou, Guangxin
    Rao, Qiu
    Wang, Xiaoxia
    Zhou, Xiaodie
    Lomberk, Gwen
    Liu, Bing
    Zhao, Jianning
    Ge, Jingping
    Zhou, Wenquan
    Chu, Xiaoyuan
    Chen, Cheng
    Zhou, Xuhui
    Wang, Linhui
    Guan, Kunliang
    Qu, Le
    SCIENCE ADVANCES, 2021, 7 (05):
  • [42] A Genome-Wide CRISPR-Cas9 Screen Identifies Importin-β11 as a Required Factor for β-catenin Signaling in Colon Cancer
    Mis, Monika
    Steinhart, Zachary
    Angers, Stephane
    FASEB JOURNAL, 2018, 32 (01):
  • [43] Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway
    Maeda, Takahiro
    CANCER SCIENCE, 2018, 109 : 812 - 812
  • [44] The new frontier of genome engineering with CRISPR-Cas9
    Doudna, Jennifer A.
    Charpentier, Emmanuelle
    SCIENCE, 2014, 346 (6213) : 1077 - +
  • [45] Genome-wide CRISPR-Cas9 screen analyzed by SLIDER identifies network of repressor complexes that regulate TRIM24
    Patel, Lalit R.
    Stratton, Sabrina A.
    Mclaughlin, Megan
    Krause, Patrick
    Allton, Kendra
    Rivas, Andres Lopez
    Barbosa, Daniela
    Hart, Traver
    Barton, Michelle C.
    ISCIENCE, 2023, 26 (07)
  • [46] CIRCLE-seq: A highly sensitive in vitro screen for genome-wide CRISPR-Cas9 nuclease off-targets
    Tsai S.Q.
    Nguyen N.T.
    Malagon-Lopez J.
    Topkar V.V.
    Aryee M.J.
    Joung J.K.
    Nature Methods, 2017, 14 (6) : 607 - 614
  • [47] Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma
    Tsiami, Foteini
    Lago, Chiara
    Pozza, Noemi
    Piccioni, Federica
    Zhao, Xuesong
    Luelsberg, Fabienne
    Root, David E.
    Tiberi, Luca
    Kool, Marcel
    Schittenhelm, Jens
    Bandopadhayay, Pratiti
    Segal, Rosalind A.
    Tabatabai, Ghazaleh
    Merk, Daniel J.
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2024, 12 (01):
  • [48] Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring
    Dong, Yan
    Li, Haimei
    Zhao, Liang
    Koopman, Peter
    Zhang, Feng
    Huang, Johnny X.
    G3-GENES GENOMES GENETICS, 2019, 9 (11): : 3645 - 3651
  • [49] The genomic landscape of sensitivity to arsenic trioxide uncovered by genome-wide CRISPR-Cas9 screening
    Chen, Jun-Zhu
    Wang, Li-Na
    Luo, Xue-Qun
    Tang, Yan-Lai
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [50] Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy
    Lek, Angela
    Zhang, Yuanfan
    Woodman, Keryn G.
    Huang, Shushu
    DeSimone, Alec M.
    Cohen, Justin
    Ho, Vincent
    Conner, James
    Mead, Lillian
    Kodani, Andrew
    Pakula, Anna
    Sanjana, Neville
    King, Oliver D.
    Jones, Peter L.
    Wagner, Kathryn R.
    Lek, Monkol
    Kunkel, Louis M.
    SCIENCE TRANSLATIONAL MEDICINE, 2020, 12 (536)
12345