Solid-phase synthesis of 3H-quinazolin-4-ones based on an aza Wittig-mediated annulation strategy

被引：1

作者：

Villalgordo, JM ^{[1
]}

Obrecht, D ^{[1
]}

Chucholowsky, A ^{[1
]}

机构：

[1] F Hoffmann La Roche AG, Pharma Res, CH-4002 Basel, Switzerland

来源：

SYNLETT | 1998年 / 12期

关键词：

solid-phase synthesis; polymer-bound carbodiimides; quinazolinone library; aza Wittig-mediated cyclization; multidirectional cleavage;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aza Wittig-mediated annulation provides a highly efficient and straightforward strategy for the parallel synthesis of 3H-quinazolin-4-ones on solid support. The products were recovered in good yields and exhibited excellent purities.

引用

页码：1405 / 1407

页数：3

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