Regulatory T cells and IL-10 in allergic inflammation

被引:127
|
作者
Hawrylowicz, CM [1 ]
机构
[1] Kings Coll London, MRC, London SE1 9RT, England
[2] Kings Coll London, Asthma UK Ctr Allerg Mech Asthma, London SE1 9RT, England
来源
JOURNAL OF EXPERIMENTAL MEDICINE | 2005年 / 202卷 / 11期
关键词
D O I
10.1084/jem.20052211
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recent studies suggest that human regulatory T ( T reg) cells protect against the development of allergic and asthmatic disease and that their function is impaired during active disease. Two new studies contribute to our understanding of the role that T reg cells play in the control of allergic airway disease in mice. However, these studies also highlight several outstanding questions in the field.
引用
收藏
页码:1459 / 1463
页数:5
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