Synthesis and antimicrobial activities of some new 4H-1,4-benzothiazines

被引：0
|
作者：
Dixit, Rahul [1 ]
Dixit, Yogesh
Gautam, Naveen
Gautam, D. C.
机构：
[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India
[2] LBS Govt PG Coll, Jaipur 303108, Rajasthan, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 16卷 / 04期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Synthesis of substituted 4H-1,4-benzothiazines (4) by the condensation of 2-amino-5-bromo-3-methyl/2-amino-4-fluoro/2-amino-3-isopropylbenzenethiol with beta-diketones/beta-ketoesters in dimethylsulfoxide, which caused oxidative cyclization is being reported. Substituted 4H-1,4-benzothiazine sulfones (5) have been synthesized by oxidation of 4H-benzothiazines (4) on refluxing with 30% hydrogen peroxide in gl acetic acid. Synthesized compound have been characterized by IR, H-1 NMR, Mass spectra, elemental analysis and screened for antimicrobial activity.
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页码：391 / 394
页数：4
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