Menorrhagia;
Acquired von Willebrand Syndrome;
Hypothyroidism;
PREVALENCE;
D O I:
暂无
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
Eighteen-year-old patient presented with complaint of menorrhagia since menarche, along with severe anaemia. Investigations showed low vWF factor levels for her "B" Rh "+"ve- non-'O' blood group, without any family history of bleeding disorder or thyroid disfunction, further probing in thyroid function revealed severe hypothyroidism, though clinical examination did not show any signs suggestive of hypothyroidism. Oral Thyroxin for correction of hypothyroidism helped to stop menorrhagia effectively, showing consistency in diagnosis of Acquired von Willebrand Factor deficiency which in turn resulted in Factor VIII dysfunction secondary to hypothyroidism.
机构:
Fdn IRCCS Ca Granda Osped Maggiore Policlin A Bla, Bianchi Bonomi Hemophilia & Thrombosis Ctr, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin A Bla, Bianchi Bonomi Hemophilia & Thrombosis Ctr, Milan, Italy
机构:
Univ Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Ragni, Margaret V.
Seaman, Craig D.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Med Ctr, Pittsburgh, PA USA
Hemophilia Ctr Western PA, Pittsburgh, PA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Seaman, Craig D.
Gilligan, Diana
论文数: 0引用数: 0
h-index: 0
机构:
Suny Upstate Med Ctr, Syracuse, NY 13210 USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Gilligan, Diana
Philipp, Claire S.
论文数: 0引用数: 0
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机构:
Rutgers State Univ, UMDNJ Robert Wood Johnson Med Sch, Med, New Brunswick, NJ USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Philipp, Claire S.
Neff, Anne T.
论文数: 0引用数: 0
h-index: 0
机构:
Cleveland Clin, Cleveland, OH 44106 USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Neff, Anne T.
Sidonio, Robert F., Jr.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Healthcare Atlanta, Hemophilia Georgia Ctr Bleeding & Clotting Disord, Aflac Canc & Blood Disorders Ctr, Decatur, GA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Sidonio, Robert F., Jr.
Kuriakose, Philip
论文数: 0引用数: 0
h-index: 0
机构:
Wayne State Univ, Div Hematol & Oncol, Henry Ford Hosp, Detroit, MI USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Kuriakose, Philip
Wang, Tzu-Fei
论文数: 0引用数: 0
h-index: 0
机构:
Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Wang, Tzu-Fei
Malec, Lynn M.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Pittsburgh, Dept Pediat, Div Hematol, Pittsburgh, PA 15213 USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Malec, Lynn M.
Pruthi, Rajiv K.
论文数: 0引用数: 0
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机构:
Mayo Clin, Div Hematol, Rochester, MN USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Pruthi, Rajiv K.
Majerus, Elaine
论文数: 0引用数: 0
h-index: 0
机构:
Washington Univ, Sch Med, St Louis, MO USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Majerus, Elaine
Rodgers, George M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Med Ctr, Salt Lake City, UT USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Rodgers, George M.
Nance, Danielle
论文数: 0引用数: 0
h-index: 0
机构:
Banner MD Anderson Canc Ctr, Gilbert, AZ USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Nance, Danielle
Hwang, Nina
论文数: 0引用数: 0
h-index: 0
机构:
CIBD, Orange, CA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Hwang, Nina
Konkle, Barbara A.
论文数: 0引用数: 0
h-index: 0
机构:
Bloodworks Northwest, Seattle, WA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Konkle, Barbara A.
Leavitt, Andrew D.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Dept Lab Med, San Francisco, CA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Leavitt, Andrew D.
Lasky, Joseph
论文数: 0引用数: 0
h-index: 0
机构:
Cure 4 Kids Fdn, Las Vegas, NV USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Lasky, Joseph
Wheeler, Allison P.
论文数: 0引用数: 0
h-index: 0
机构:
Vanderbilt Univ, Dept Pathol Microbiol & Immunol, 221 Kirkland Hall, Nashville, TN 37235 USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Wheeler, Allison P.
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机构:
Kulkarni, Roshni
Singleton, Tammuella
论文数: 0引用数: 0
h-index: 0
机构:
Mississippi Ctr Adv Med, Madison, MS USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Singleton, Tammuella
Ivanco, Dana
论文数: 0引用数: 0
h-index: 0
机构:
Hemophilia Ctr Western PA, Inst Transfus Med, Pittsburgh, PA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Ivanco, Dana
Youm, Elynna
论文数: 0引用数: 0
h-index: 0
机构:
Hemophilia Ctr Western PA, Inst Transfus Med, Pittsburgh, PA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Youm, Elynna
Koerbel, Glory
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Ctr Res Hlth Care Data Ctr, Pittsburgh, PA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Koerbel, Glory
Rothenberger, Scott
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Ctr Res Hlth Care Data Ctr, Pittsburgh, PA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA
Rothenberger, Scott
Rubio, Doris M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Ctr Res Hlth Care Data Ctr, Pittsburgh, PA USAUniv Pittsburgh, Sch Med, Dept Med & Clin & Translat Res, Pittsburgh, PA USA