Design and structure activity relationships of highly potent and bioavailable imidazolinone FASN KR domain inhibitors

被引：0
|
作者：
Bignan, G. [1 ]
Alexander, R. [1 ]
Bischoff, J. [1 ]
Connolly, P. [1 ]
Cummings, M. [1 ]
De Breucker, S. [2 ]
Esser, N. [2 ]
Fraiponts, E. [2 ]
Gilissen, R. [2 ]
Grasberger, B. [1 ]
Janssens, B. [2 ]
Lu, T. [1 ]
Ludovici, D. [1 ]
Meerpoel, L. [2 ]
Meyer, C. [3 ]
Parker, M. [1 ]
Peeters, D. [2 ]
Rocaboy, C. [4 ]
Schubert, C. [1 ]
Smans, K. [2 ]
机构：
[1] Janssen, Oncol, Spring House, PA USA
[2] Janssen, Oncol, Beerse, Belgium
[3] Janssen, Oncol, Val De Reuil, France
[4] VillaPharma Res, Chem, Murcia, Spain
来源：
EUROPEAN JOURNAL OF CANCER | 2014年 / 50卷
关键词：
D O I：
10.1016/S0959-8049(14)70556-8
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
430
引用
收藏
页码：141 / 142
页数：2
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