Preclinical evaluation of combretastatin A4 phosphate: A drug which selectively damages tumor neovasculature

被引:0
|
作者
Chaplin, DJ
Hill, SA
Pettit, GR
机构
[1] Mt Vernon Hosp, Canc Res Trust, Gray Lab, Tumor Microcirculat Grp, Northwood HA6 2JR, Middx, England
[2] Arizona State Univ, Dept Chem, Tempe, AZ 85287 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
291
引用
收藏
页码:77 / 77
页数:1
相关论文
共 50 条
  • [31] Combretastatin A4 dimers: design, synthesis and biological evaluation.
    Casely-Hayford, M. A.
    Omobolaji, T. A.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2010, 62 (10) : 1363 - 1364
  • [32] Treatment of Rodent Liver Tumor With Combretastatin A4 Phosphate Noninvasive Therapeutic Evaluation Using Multiparametric Magnetic Resonance Imaging in Correlation With Microangiography and Histology
    Wang, Huaijun
    Sun, Xihe
    Chen, Feng
    De Keyzer, Frederik
    Yu, Jie
    Landuyt, Willy
    Vandecaveye, Vincent
    Peeters, Ronald
    Bosmans, Hilde
    Hermans, Robert
    Marchal, Guy
    Ni, Yicheng
    INVESTIGATIVE RADIOLOGY, 2009, 44 (01) : 44 - 53
  • [33] Bromoalkyloxy derivatives of combretastatin A4: Synthesis and biological evaluation[p].
    Ngassam, Lembe K.
    Anning, Edward
    Agyekum, Kweku
    Acquah, Collins
    Casely-Hayford, Maxwell A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [34] Combretastatin A4 Disodium Phosphate Forms Aggregates In Solution Leading To Exciton Transfer
    Venegas, Berenice
    Kiani, Mohammad F.
    Chong, Parkson L-G.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 401A - 401A
  • [35] Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate
    Anderson, HL
    Yap, JT
    Miller, MP
    Robbins, A
    Jones, T
    Price, PM
    JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (15) : 2823 - 2830
  • [36] Combretastatin A4 Phosphate Induces Programmed Cell Death in Vascular Endothelial Cells
    Ding, Xueqiang
    Zhang, Zhaoqiang
    Li, Su
    Wang, Anxun
    ONCOLOGY RESEARCH, 2011, 19 (07) : 303 - 309
  • [37] Combretastatin A-4 phosphate an agent that displays potent and selective toxicity toward tumour neovasculature.
    Chaplin, DJ
    Hill, SA
    Dougherty, GJ
    Prise, VE
    Tozer, GM
    Pettit, R
    HUMAN GENE THERAPY, 1999, 10 (05) : 840 - 840
  • [38] Pretreatment with tadalafil attenuates cardiotoxicity induced by combretastatin A4 disodium phosphate in rats
    Nagashima, Yoshiyasu
    Tochinai, Ryota
    Sekizawa, Shin-ichi
    Kato, Daiki
    Nakagawa, Takayuki
    Tsuru, Yoshiharu
    Tatewaki, Yasuko
    Mutoh, Tatsushi
    Taki, Yasuyuki
    Kuwahara, Masayoshi
    JOURNAL OF TOXICOLOGIC PATHOLOGY, 2023, 36 (03) : 151 - 158
  • [39] Novel vascular targeting/disrupting agents: Combretastatin A4 phosphate and related compounds
    Cooney M.M.
    Ortiz J.
    Bukowski R.M.
    Remick S.C.
    Current Oncology Reports, 2005, 7 (2) : 90 - 95
  • [40] Diaryl Isoxazole Analog of Combretastatin A4 (A Promising Substance for an Antitumor Drug
    Nemtsova, E. R.
    Morozova, N. B.
    Plyutinskaya, A. D.
    Noev, A. N.
    Pankratov, A. A.
    Demchuk, D. V.
    Krylov, S. S.
    Semenov, V. V.
    Shegay, P. V.
    Kaprin, A. D.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2025, 58 (10) : 1469 - 1474