Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT®) for the detection of malaria

被引：36
|
作者：
Pattanasin, S. [1 ]
Proux, S. [1 ]
Chompasuk, D. [1 ]
Luwiradaj, K. [1 ]
Jacquier, P. [4 ]
Looareesuwan, S. [2 ]
Nosten, F. [1 ,2 ,3 ]
机构：
[1] SMRU, St Louis, MO 63110 USA
[2] Mahidol Univ, Fac Trop Med, Bangkok, Thailand
[3] John Radcliffe Hosp, Ctr Trop Med, Oxford, England
[4] DiaMed, Basel, Switzerland
来源：
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2003年 / 97卷 / 06期
基金：
英国惠康基金;
关键词：
malaria; Plasmodium falciparum; Plasmodium lactate dehydrogenase; histidine-rich protein II;
D O I：
10.1016/S0035-9203(03)80100-1
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The new OptiMAL-IT (R) rapid diagnostic test for malaria was evaluated in 271 patients in Thailand with uncomplicated malaria between June and July 2002. The sensitivity and specificity for the diagnosis of Plasmodium falciparum parasites were 88% and 92%, respectively. For species other than P. falciparum, the sensitivity was 65% and specificity was 99%. The performance of the new test decreased markedly at low levels of parasitaemia.
引用
收藏
页码：672 / 674
页数：3
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