On age-dependent bone remodeling

被引:12
|
作者
Papastavrou, Areti [1 ]
Schmidt, Ina [1 ]
Deng, Kefu [2 ]
Steinmann, Paul [2 ]
机构
[1] Nuremberg Tech, Fac Mech Engn, Kesslerpl 12, D-90489 Nurnberg, Germany
[2] Univ Erlangen Nurnberg, Chair Appl Mech, Egerlandstr 5, D-91058 Erlangen, Germany
关键词
Bone remodeling; Density change; Growth; Finite element method; Adaption; SIMULATIONS; STABILITY; BEHAVIOR;
D O I
10.1016/j.jbiomech.2020.109701
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A number of previous studies have investigated the possibilities of modelling the change in density of bones. Remodeling can be formulated at the constitutive or the kinematic level. In this work we introduce a formulation for the density growth process which takes not only the mechanical stimulus into account but also the influence of age on the evolution of growth. We demonstrate the implementation in the context of the finite element method. This novel approach is illustrated for a simple uniaxial extension test and is verified against previous numerical results. Moreover, two further physiologically motivated examples are performed. The results of the proposed modified model show excellent agreement with comparable results from literature and are promising for the application to real-life problems. (C) 2020 Elsevier Ltd. All rights reserved.
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页数:10
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