Phenome-Wide Association Study of Severe COVID-19 Genetic Risk Variants

被引:10
|
作者
Regan, Jessica A. [1 ,2 ]
Abdulrahim, Jawan W. [1 ,2 ]
Bihlmeyer, Nathan A. [1 ]
Haynes, Carol [1 ]
Kwee, Lydia Coulter [1 ]
Patel, Manesh R. [2 ,3 ]
Shah, Svati H. [1 ,2 ,3 ]
机构
[1] Duke Mol Physiol Inst, Durham, NC USA
[2] Duke Univ, Dept Med, Durham, NC USA
[3] Duke Clin Res Inst, Durham, NC USA
来源
关键词
cardiovascular disease; COVID; 19; genetics; inflammation;
D O I
10.1161/JAHA.121.024004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women
    Renato Polimanti
    Henry R Kranzler
    Joel Gelernter
    Neuropsychopharmacology, 2016, 41 : 2688 - 2696
  • [22] A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects
    Shameer, Khader
    Denny, Joshua C.
    Ding, Keyue
    Jouni, Hayan
    Crosslin, David R.
    de Andrade, Mariza
    Chute, Christopher G.
    Peissig, Peggy
    Pacheco, Jennifer A.
    Li, Rongling
    Bastarache, Lisa
    Kho, Abel N.
    Ritchie, Marylyn D.
    Masys, Daniel R.
    Chisholm, Rex L.
    Larson, Eric B.
    McCarty, Catherine A.
    Roden, Dan M.
    Jarvik, Gail P.
    Kullo, Iftikhar J.
    HUMAN GENETICS, 2014, 133 (01) : 95 - 109
  • [23] The Phenome-Wide Distribution of Genetic Variance
    Blows, Mark W.
    Allen, Scott L.
    Collet, Julie M.
    Chenoweth, Stephen F.
    McGuigan, Katrina
    AMERICAN NATURALIST, 2015, 186 (01): : 15 - 30
  • [24] Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women
    Polimanti, Renato
    Kranzler, Henry R.
    Gelernter, Joel
    NEUROPSYCHOPHARMACOLOGY, 2016, 41 (11) : 2688 - 2696
  • [25] Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
    Schmidt, Amand F.
    Holmes, Michael V.
    Preiss, David
    Swerdlow, Daniel I.
    Denaxas, Spiros
    Fatemifar, Ghazaleh
    Faraway, Rupert
    Finan, Chris
    Valentine, Dennis
    Fairhurst-Hunter, Zammy
    Hartwig, Fernando Pires
    Horta, Bernardo Lessa
    Hypponen, Elina
    Power, Christine
    Moldovan, Max
    van Iperen, Erik
    Hovingh, Kees
    Demuth, Ilja
    Norman, Kristina
    Steinhagen-Thiessen, Elisabeth
    Demuth, Juri
    Bertram, Lars
    Lill, Christina M.
    Coassin, Stefan
    Willeit, Johann
    Kiechl, Stefan
    Willeit, Karin
    Mason, Dan
    Wright, John
    Morris, Richard
    Wanamethee, Goya
    Whincup, Peter
    Ben-Shlomo, Yoav
    McLachlan, Stela
    Price, Jackie F.
    Kivimaki, Mika
    Welch, Catherine
    Sanchez-Galvez, Adelaida
    Marques-Vidal, Pedro
    Nicolaides, Andrew
    Panayiotou, Andrie G.
    Onland-Moret, N. Charlotte
    van der Schouw, Yvonne T.
    Matullo, Giuseppe
    Fiorito, Giovanni
    Guarrera, Simonetta
    Sacerdote, Carlotta
    Wareham, Nicholas J.
    Langenberg, Claudia
    Scott, Robert A.
    BMC CARDIOVASCULAR DISORDERS, 2019, 19 (01)
  • [26] A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects
    Khader Shameer
    Joshua C. Denny
    Keyue Ding
    Hayan Jouni
    David R. Crosslin
    Mariza de Andrade
    Christopher G. Chute
    Peggy Peissig
    Jennifer A. Pacheco
    Rongling Li
    Lisa Bastarache
    Abel N. Kho
    Marylyn D. Ritchie
    Daniel R. Masys
    Rex L. Chisholm
    Eric B. Larson
    Catherine A. McCarty
    Dan M. Roden
    Gail P. Jarvik
    Iftikhar J. Kullo
    Human Genetics, 2014, 133 : 95 - 109
  • [27] Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
    Amand F. Schmidt
    Michael V. Holmes
    David Preiss
    Daniel I. Swerdlow
    Spiros Denaxas
    Ghazaleh Fatemifar
    Rupert Faraway
    Chris Finan
    Dennis Valentine
    Zammy Fairhurst-Hunter
    Fernando Pires Hartwig
    Bernardo Lessa Horta
    Elina Hypponen
    Christine Power
    Max Moldovan
    Erik van Iperen
    Kees Hovingh
    Ilja Demuth
    Kristina Norman
    Elisabeth Steinhagen-Thiessen
    Juri Demuth
    Lars Bertram
    Christina M. Lill
    Stefan Coassin
    Johann Willeit
    Stefan Kiechl
    Karin Willeit
    Dan Mason
    John Wright
    Richard Morris
    Goya Wanamethee
    Peter Whincup
    Yoav Ben-Shlomo
    Stela McLachlan
    Jackie F. Price
    Mika Kivimaki
    Catherine Welch
    Adelaida Sanchez-Galvez
    Pedro Marques-Vidal
    Andrew Nicolaides
    Andrie G. Panayiotou
    N. Charlotte Onland-Moret
    Yvonne T. van der Schouw
    Giuseppe Matullo
    Giovanni Fiorito
    Simonetta Guarrera
    Carlotta Sacerdote
    Nicholas J. Wareham
    Claudia Langenberg
    Robert A. Scott
    BMC Cardiovascular Disorders, 19
  • [28] A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program
    Verma, Anurag
    Tsao, Noah L.
    Thomann, Lauren O.
    Ho, Yuk-Lam
    Iyengar, Sudha K.
    Luoh, Shiuh-Wen
    Carr, Rotonya
    Crawford, Dana C.
    Efird, Jimmy T.
    Huffman, Jennifer E.
    Hung, Adriana
    Ivey, Kerry L.
    Levin, Michael G.
    Lynch, Julie
    Natarajan, Pradeep
    Pyarajan, Saiju
    Bick, Alexander G.
    Costa, Lauren
    Genovese, Giulio
    Hauger, Richard
    Madduri, Ravi
    Pathak, Gita A.
    Polimanti, Renato
    Voight, Benjamin
    Vujkovic, Marijana
    Zekavat, Seyedeh Maryam
    Zhao, Hongyu
    Ritchie, Marylyn D.
    Chang, Kyong-Mi
    Cho, Kelly
    Casas, Juan P.
    Tsao, Philip S.
    Gaziano, J. Michael
    O'Donnell, Christopher
    Damrauer, Scott M.
    Liao, Katherine P.
    PLOS GENETICS, 2022, 18 (04):
  • [29] Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosterone
    Isabelle M. McGrath
    Grant W. Montgomery
    Sally Mortlock
    BMC Medicine, 21
  • [30] Phenome-wide association of 1809 phenotypes and COVID-19 disease progression in the Veterans Health Administration Million Veteran Program
    Song, Rebecca J.
    Ho, Yuk-Lam
    Schubert, Petra
    Park, Yojin
    Posner, Daniel
    Lord, Emily M.
    Costa, Lauren
    Gerlovin, Hanna
    Kurgansky, Katherine E.
    Anglin-Foote, Tori
    DuVall, Scott
    Huffman, Jennifer E.
    Pyarajan, Saiju
    Beckham, Jean C.
    Chang, Kyong-Mi
    Liao, Katherine P.
    Djousse, Luc
    Gagnon, David R.
    Whitbourne, Stacey B.
    Ramoni, Rachel
    Muralidhar, Sumitra
    Tsao, Philip S.
    O'Donnell, Christopher J.
    Gaziano, John Michael
    Casas, Juan P.
    Cho, Kelly
    PLOS ONE, 2021, 16 (05):