COVID-19 mRNA vaccine effectiveness (second and first booster dose) against hospitalisation and death during Omicron BA.5 circulation: cohort study based on electronic health records, Portugal, May to July 2022

被引:562
|
作者
Kislaya, Irina [1 ,2 ]
Machado, Ausenda [1 ,2 ]
Magalhaes, Sarah
Rodrigues, Ana Paula
Franco, Rafael
Leitek, Pedro Pinto [3 ,4 ]
Dias, Carlos Matias [1 ,2 ]
Nunes, Baltazar [1 ,2 ]
机构
[1] Inst Nacl Sailde Doutor Ricardo Jorge, Dept Epidemiol, Lisbon, Portugal
[2] Univ NOVA Lisboa, Ctr Invest Saude Publ, Escola Nacl Saude Publ, Lisbon, Portugal
[3] Serv Partilhados Minist Saude, Lisbon, Portugal
[4] Direcao Servi Informacao & Analise, Direcao Geral Saude, Lisbon, Portugal
关键词
D O I
10.2807/1560-7917.ES.2022.27.37.2200697
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We measured vaccine effectiveness (VE) against COVID-19-related severe outcomes in elderly people in Portugal between May and July 2022. In 2 80 year -olds, the second booster dose VE was 81% (95% CI: 75-85) and 82% (95% CI: 77-85), respectively, against COVID-19-related hospitalisation and death. The first booster dose VE was 63% (95% CI: 55-70) in 2 80 year -olds and 74% (95% CI: 66-80) in 60-79 year-olds against hospitalisation, and 63% (95% CI: 57-69) and 65% (95% CI: 54-74) against death.
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页数:6
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