COVID-19 mRNA vaccine effectiveness (second and first booster dose) against hospitalisation and death during Omicron BA.5 circulation: cohort study based on electronic health records, Portugal, May to July 2022

被引:562
|
作者
Kislaya, Irina [1 ,2 ]
Machado, Ausenda [1 ,2 ]
Magalhaes, Sarah
Rodrigues, Ana Paula
Franco, Rafael
Leitek, Pedro Pinto [3 ,4 ]
Dias, Carlos Matias [1 ,2 ]
Nunes, Baltazar [1 ,2 ]
机构
[1] Inst Nacl Sailde Doutor Ricardo Jorge, Dept Epidemiol, Lisbon, Portugal
[2] Univ NOVA Lisboa, Ctr Invest Saude Publ, Escola Nacl Saude Publ, Lisbon, Portugal
[3] Serv Partilhados Minist Saude, Lisbon, Portugal
[4] Direcao Servi Informacao & Analise, Direcao Geral Saude, Lisbon, Portugal
关键词
D O I
10.2807/1560-7917.ES.2022.27.37.2200697
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We measured vaccine effectiveness (VE) against COVID-19-related severe outcomes in elderly people in Portugal between May and July 2022. In 2 80 year -olds, the second booster dose VE was 81% (95% CI: 75-85) and 82% (95% CI: 77-85), respectively, against COVID-19-related hospitalisation and death. The first booster dose VE was 63% (95% CI: 55-70) in 2 80 year -olds and 74% (95% CI: 66-80) in 60-79 year-olds against hospitalisation, and 63% (95% CI: 57-69) and 65% (95% CI: 54-74) against death.
引用
收藏
页数:6
相关论文
共 41 条
  • [1] Effectiveness of the booster dose of inactivated COVID-19 vaccine against Omicron BA.5 infection: a matched cohort study of adult close contacts
    Zeng, Ting
    Lu, Yaoqin
    Zhao, Yanji
    Guo, Zihao
    Sun, Shengzhi
    Teng, Zhidong
    Tian, Maozai
    Wang, Jun
    Li, Shulin
    Fan, Xucheng
    Wang, Weiming
    Cai, Yongli
    Liao, Gengze
    Liang, Xiao
    He, Daihai
    Wang, Kai
    Zhao, Shi
    RESPIRATORY RESEARCH, 2023, 24 (01)
  • [2] Effectiveness of the booster dose of inactivated COVID-19 vaccine against Omicron BA.5 infection: a matched cohort study of adult close contacts
    Ting Zeng
    Yaoqin Lu
    Yanji Zhao
    Zihao Guo
    Shengzhi Sun
    Zhidong Teng
    Maozai Tian
    Jun Wang
    Shulin Li
    Xucheng Fan
    Weiming Wang
    Yongli Cai
    Gengze Liao
    Xiao Liang
    Daihai He
    Kai Wang
    Shi Zhao
    Respiratory Research, 24
  • [3] Neutralization of Omicron subvariants BA.1 and BA.5 by a booster dose of COVID-19 mRNA vaccine in a Japanese nursing home cohort
    Itamochi, Masae
    Yazawa, Shunsuke
    Inasaki, Noriko
    Saga, Yumiko
    Yamazaki, Emiko
    Shimada, Takahisa
    Tamura, Kosuke
    Maenishi, Emi
    Isobe, Junko
    Nakamura, Masahiko
    Takaoka, Misuzu
    Sasajima, Hitoshi
    Kawashiri, Chikako
    Tani, Hideki
    Oishi, Kazunori
    VACCINE, 2023, 41 (13) : 2234 - 2242
  • [4] Effectiveness of first and second COVID-19 mRNA vaccine monovalent booster doses during a period of circulation of Omicron variant sublineages: December 2021-July 2022
    Petrie, Joshua G.
    King, Jennifer P.
    McClure, David L.
    Rolfes, Melissa A.
    Meece, Jennifer K.
    Pattinson, David
    Neumann, Gabriele
    Kawaoka, Yoshihiro
    Belongia, Edward A.
    McLean, Huong Q.
    INFLUENZA AND OTHER RESPIRATORY VIRUSES, 2023, 17 (03)
  • [5] Effectiveness of A Fourth Dose of COVID-19 mRNA Vaccine in the Elderly Population During the Omicron BA.2 and BA.5 Circulation: A Nationwide Cohort Study in Korea (K-COVE)
    Park, Seon Kyeong
    Choe, Young June
    Jang, Eun Jung
    Kim, Ryu Kyung
    Lim, Do-Sang
    Yi, Seonju
    Lee, Sangwon
    Kwon, Geun-Yong
    Shin, Jee Yeon
    Choi, Sang-Yoon
    Jeong, Mi Jin
    Park, Young-Joon
    OPEN FORUM INFECTIOUS DISEASES, 2023, 10 (03):
  • [6] Estimation of COVID-19 mRNA Vaccine Effectiveness and COVID-19 Illness and Severity by Vaccination Status During Omicron BA.4 and BA.5 Sublineage Periods
    Link-Gelles, Ruth
    Levy, Matthew E.
    Natarajan, Karthik
    Reese, Sarah E.
    Naleway, Allison L.
    Grannis, Shaun J.
    Klein, Nicola P.
    DeSilva, Malini B.
    Ong, Toan C.
    Gaglani, Manjusha
    Hartmann, Emily
    Dickerson, Monica
    Stenehjem, Edward
    Kharbanda, Anupam B.
    Han, Jungmi
    Spark, Talia L.
    Irving, Stephanie A.
    Dixon, Brian E.
    Zerbo, Ousseny
    McEvoy, Charlene E.
    Rao, Suchitra
    Raiyani, Chandni
    Sloan-Aagard, Chantel
    Patel, Palak
    Dascomb, Kristin
    Uhlemann, Anne-Catrin
    Dunne, Margaret M.
    Fadel, William F.
    Lewis, Ned
    Barron, Michelle A.
    Murthy, Kempapura
    Nanez, Juan
    Griggs, Eric P.
    Grisel, Nancy
    Annavajhala, Medini K.
    Akinseye, Akintunde
    Valvi, Nimish R.
    Goddard, Kristin
    Mamawala, Mufaddal
    Arndorfer, Julie
    Yang, Duck-Hye
    Embi, Peter J.
    Fireman, Bruce
    Ball, Sarah W.
    Tenforde, Mark W.
    JAMA NETWORK OPEN, 2023, 6 (03) : E232598
  • [7] Effectiveness of COVID-19 booster vaccination, morbidity and absenteeism among healthcare personnel during the 2022-2023 season dominated by Omicron BA.5 and BA.2 subvariants
    Maltezou, Helena C.
    Gamaletsou, Maria N.
    Giannouchos, Theodoros, V
    Koukou, Dimitra-Maria
    Sourri, Flora
    Karapanou, Amalia
    Lemonakis, Nikolaos
    Souliotis, Kyriakos
    Lourida, Athanasia
    Panagopoulos, Periklis
    Hatzigeorgiou, Dimitrios
    Sipsas, Nikolaos, V
    VACCINE, 2024, 42 (17) : 3693 - 3698
  • [8] Effectiveness of a Second COVID-19 Vaccine Booster Dose Against Infection, Hospitalization, or Death Among Nursing Home Residents-19 States, March 29-July 25, 2022
    McConeghy, Kevin W.
    White, Elizabeth M.
    Blackman, Carolyn
    Santostefano, Christopher M.
    Lee, Yoojin
    Rudolph, James L.
    Canaday, David
    Zullo, Andrew R.
    Jernigan, John A.
    Pilishvili, Tamara
    Mor, Vincent
    Gravenstein, Stefan
    MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2022, 71 (39): : 1235 - 1238
  • [9] Effectiveness of a Third Dose of COVID-19 mRNA Vaccine During the Omicron BA.1-and BA.2-Predominant Periods in Japan: The VENUS Study
    Mimura, Wataru
    Ishiguro, Chieko
    Maeda, Megumi
    Murata, Fumiko
    Fukuda, Haruhisa
    OPEN FORUM INFECTIOUS DISEASES, 2022, 9 (12):
  • [10] Effectiveness of mRNA-1273 bivalent (original and omicron BA.4/BA.5) COVID-19 vaccine against hospitalizations for COVID-19, medically attended SARS-CoV-2 infections, and COVID-19 hospital deaths in the United States
    Tseng, Hung Fu
    Ackerson, Bradley K.
    Sy, Lina S.
    Tubert, Julia E.
    Luo, Yi
    Qiu, Sijia
    Bruxvoort, Katia J.
    Lee, Gina S.
    Ku, Jennifer H.
    Florea, Ana
    Takhar, Harpreet S.
    Zhou, Cindy Ke
    Esposito, Daina
    Chavers, Scott
    Talarico, Carla A.
    Qian, Lei
    PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2023, 32 : 609 - 609