Autophagy Inhibition Potentiates Ruxolitinib-Induced Apoptosis in JAK2V617F Cells

被引：1
|
作者：
Machado-Neto, Joao Agostinho [1 ,2 ]
Coelho-Silva, Juan Luiz [1 ]
de Souza Santos, Fabio Pires [3 ]
Scheucher, Priscila Santos [1 ]
Campregher, Paulo Vidal [3 ]
Hamerschlak, Nelson [3 ]
Rego, Eduardo Magalhaes [1 ,4 ]
Traina, Fabiola [1 ]
机构：
[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Ribeirao Preto, Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, Dept Pharmacol, Sao Paulo, Brazil
[3] Albert Einstein Hosp, Einsteins Teaching & Res Inst, Sao Paulo, Brazil
[4] Univ Sao Paulo, Sch Med, Sao Paulo, Brazil
来源：
BLOOD | 2018年 / 132卷
关键词：
D O I：
10.1182/blood-2018-99-119651
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1788
引用
收藏
页数：2
相关论文
共 50 条
  • [31] JAK2V617F complete molecular remission in polycythemia vera/essential thrombocythemia patients treated with ruxolitinib
    Pieri, Lisa
    Pancrazzi, Alessandro
    Pacilli, Annalisa
    Rabuzzi, Claudia
    Rotunno, Giada
    Fanelli, Tiziana
    Guglielmelli, Paola
    Fjerza, Rajmonda
    Paoli, Chiara
    Verstovsek, Srdan
    Vannucchi, Alessandro M.
    BLOOD, 2015, 125 (21) : 3352 - 3353
  • [32] JAK2V617F: more than a clonal marker?
    Tefferi, Ayalew
    LEUKEMIA & LYMPHOMA, 2009, 50 (02) : 154 - 155
  • [33] JAK2V617F mutation and thrombosis in the myeloproliferative neoplasms
    Demirkan, F.
    Kalkan, S.
    Kahraman, S.
    Tunali, S.
    Katgi, A.
    Piskin, O.
    Ozcan, M. A.
    Ozsan, H. G.
    Undar, B.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2011, 9 : 890 - 890
  • [34] Effect of busulfan on JAK2V617F allele burden
    Randi, Maria Luigia
    Santarossa, Claudia
    Peroni, Edoardo
    Cosi, Elisabetta
    Duner, Elena
    Bertozzi, Irene
    Fabris, Fabrizio
    HAEMATOLOGICA, 2014, 99 (03) : E44 - E44
  • [35] Accelerated Atherosclerosis and Thrombosis in Jak2v617f Mice
    Wang, Wei
    Liu, Wenli
    Wang, Ying
    Tang, Yang
    Woods, Brittany
    Welch, Carrie
    Cai, Bishuang
    Ai, Ding
    Yang, Yong-Guang
    Silvestre, Carlos
    Soehnlein, Oliver
    Tabas, Ira
    Levine, Ross L.
    Tall, Alan R.
    Wang, Nan
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018, 38
  • [36] Is the JAK2V617F mutation detectable in healthy volunteers?
    Martinaud, Christophe
    Brisou, Patrick
    Mozziconacci, Marie-Joelle
    AMERICAN JOURNAL OF HEMATOLOGY, 2010, 85 (04) : 287 - 288
  • [37] Platelet Phenotype and Thrombosis In JAK2V617F Mice
    Lamrani, Lamia
    Lacout, Catherine
    Ollivier, Veronique
    Hoe, Benoit H. O. Tin
    Vainchenker, William
    Villeval, Jean-Luc
    Jandrot-Perrus, Martine
    BLOOD, 2011, 118 (21) : 283 - 283
  • [38] Thrombosis in Myeloproliferative Neoplasms With JAK2V617F Mutation
    Sun, Tiantian
    Zhang, Lei
    CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2013, 19 (04) : 374 - 381
  • [39] Ischaemic colitis associated with JAK2V617F mutation
    Barbieri, J.
    Duboc, H.
    Teillet, F.
    Sabate, J. M.
    Peynaud, E.
    Jouet, P.
    Coffin, B.
    GUT, 2012, 61 (05) : 784 - 785
  • [40] Lineage Restricted JAK2V617F Expression and Its Role in Thrombosis and Hemostasis; The Potential Involvement of Endothelial JAK2V617F in Clotting Abnormalities
    Hitchcock, Ian S.
    Roh, Michelle E.
    Sangkhae, Veena
    Etheridge, Leah
    Chen, Rose
    Fox, Norma E.
    Kaushansky, Kenneth
    BLOOD, 2011, 118 (21) : 758 - 758
12345